Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes Angela M. Valverde , 1 , Deborah J. Burks 2 , Isabel Fabregat 1 , Tracey L. Fisher 3 , José Carretero 2 , Morris F. White 3 and Manuel Benito 1 1 Instituto de Bioquímica/Departamento de Bioquímica y Biología Molecular II, Cent...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2003-09, Vol.52 (9), p.2239-2248
Hauptverfasser:	VALVERDE, Angela M, BUNKS, Deborah J, FABREGAT, Isabel, FISHER, Tracey L, CARRETERO, José, WHITE, Morris F, BENITO, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Animals Animals, Newborn Antibodies Antigens Antigens, Polyomavirus Transforming - genetics Associated diseases and complications Biological and medical sciences Cell Line, Transformed Development and progression Diabetes Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Fisiologia Forkhead Box Protein O1 Forkhead Transcription Factors Gene expression Genetic aspects Genetics Genètica Gluconeogenesis - physiology Glucose Glucose-6-Phosphatase - metabolism Glycogen Synthase - metabolism Glycogen Synthase Kinase 3 - metabolism Hepatocytes - cytology Hepatocytes - metabolism Hypoglycemic Agents - pharmacology Infections Insulin - pharmacology Insulin Receptor Substrate Proteins Insulin resistance Insulin Resistance - physiology Intracellular Signaling Peptides and Proteins Isoenzymes Kinases Liver Male Medical sciences Metabolism Metabolisme Mice Mice, Mutant Strains Phosphatase Phosphatidylinositol 3-Kinases - metabolism Phosphatidylinositol Phosphates - biosynthesis Phosphoenolpyruvate Carboxykinase (GTP) - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Phosphorylation Physiological aspects Physiology Pregnancy Protein Kinase C - metabolism Protein kinases Protein-Serine-Threonine Kinases Proteins Proteïnes quinases Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt Resistència a la insulina Retroviridae - genetics Signal Transduction - physiology Transcription Factors - metabolism Type 2 diabetes
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