Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI ProteinChip platform

Useful biomarkers are needed for early detection of cancers. To demonstrate the potential diagnostic usefulness of a new proteomic technology, we performed Expression Difference Mapping analysis on 39 cancer cell lines from 9 different tissues using ProteinChip technology. A protein biomarker candid...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-09, Vol.309 (1), p.18-25
Hauptverfasser:	Shiwa, Mieko, Nishimura, Yumiko, Wakatabe, Rumi, Fukawa, Ai, Arikuni, Hisashi, Ota, Hiroyuki, Kato, Yo, Yamori, Takao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarker Biomarkers, Tumor Colon - cytology Colon - metabolism Colon cancer Dose-Response Relationship, Drug Electrophoresis, Polyacrylamide Gel Expression Difference Mapping Humans Mass Spectrometry Protein Array Analysis - methods Protein Precursors - biosynthesis ProteinChip RC-MS SELDI Thymosin - analogs & derivatives Thymosin - biosynthesis Trypsin - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
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