Characterizing cellular immune response to kinetoplastid membrane protein‐11 (KMP‐11) during Leishmania (Viannia) panamensis infection using dendritic cells (DCs) as antigen presenting cells (APCs)

SUMMARY In vitro peptide binding assays and DCs pulsed with recombinant KMP‐11 (rKMP‐11) plus six 20‐mer overlapping peptides covering the entire protein of Leishmania (Viannia) panamensis (L(V)p) promastigotes were used to identify T‐cell epitopes in this protein. Such in vitro binding assays, usin...

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Veröffentlicht in:	Parasite immunology 2003-04, Vol.25 (4), p.199-209
Hauptverfasser:	Delgado, Gabriela, Parra‐López, Carlos A., Vargas, Luis Eduardo, Hoya, Rubén, Estupiñán, Mónica, Guzmán, Fanny, Torres, Angela, Alonso, Carlos, Velez, Iván Dario, Spinel, Clara, Patarroyo, Manuel E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antigen Presentation Antigens, Protozoan - genetics Binding, Competitive Case-Control Studies Cell Line Cytokines - biosynthesis Dendritic Cells - immunology Epitope Mapping Epitopes - genetics Female HLA-DR Antigens - metabolism HLA-DRB1 Chains Humans Immunity, Cellular In Vitro Techniques Leishmania guyanensis - genetics Leishmania guyanensis - immunology Leishmaniasis, Mucocutaneous - immunology Lymphocyte Activation Male Membrane Proteins - genetics Membrane Proteins - immunology Molecular Sequence Data Protozoan Proteins - genetics Protozoan Proteins - immunology T-Lymphocytes - immunology
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