Clustering of mutations inactivating a Chi recombinational hotspot

Chi sites promote Rec-mediated recombination in bacteriophage λ. Nine independent, nitrous acid-induced mutations were obtained within one of these sites, χ +C. Eight of the mutations completely inactivated the Chi site, while one mutation left partial activity. Nucleotide sequence analysis showed t...

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Veröffentlicht in:	Journal of molecular biology 1981-03, Vol.146 (3), p.275-286
Hauptverfasser:	Schultz, Dennis W., Swindle, John, Smith, Gerald R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriophage lambda - genetics Base Sequence Deoxyribonucleotides - analysis DNA Restriction Enzymes - metabolism DNA, Viral Escherichia coli - genetics Mutation Recombination, Genetic
Online-Zugang:	Volltext
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