Cerebral Gnathostomiasis as a Cause of an Extended Intracranial Bleeding
Abstract This is a report of a fourteen year old Thai-girl who presented with acute hemiparesis because of intracranial haemorrhage six weeks after immigrating to Germany. Marked blood eosinophilia and raised IgE in serum in comparison with her origin led to the suspected diagnosis of parasitosis. A...
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| Veröffentlicht in: | Klinische Pädiatrie 2003-07, Vol.215 (4), p.223-225 |
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| container_title | Klinische Pädiatrie |
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| creator | Germann, R. Schächtele, M. Neßler, G. Seitz, U. Kniehl, E. |
| description | Abstract
This is a report of a fourteen year old Thai-girl who presented with acute hemiparesis because of intracranial haemorrhage six weeks after immigrating to Germany. Marked blood eosinophilia and raised IgE in serum in comparison with her origin led to the suspected diagnosis of parasitosis. Angiography showed mycotic aneurysm typical for cerebral gnathostomiasis one of the major causes of intracranial haemorrhage in children in Thailand. This diagnosis was confirmed by detecting specific antibodies against GNATHOSTOMA SPINIGERUM in serum and CSF by Western blot. Therapy was started with albendazole and dexamethasone and the girl made a complete recovery. In case of intracranial haemorrhage cerebral gnathostomiasis should be considered if the patient originates from an endemic area. |
| doi_str_mv | 10.1055/s-2003-41401 |
| format | Article |
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This is a report of a fourteen year old Thai-girl who presented with acute hemiparesis because of intracranial haemorrhage six weeks after immigrating to Germany. Marked blood eosinophilia and raised IgE in serum in comparison with her origin led to the suspected diagnosis of parasitosis. Angiography showed mycotic aneurysm typical for cerebral gnathostomiasis one of the major causes of intracranial haemorrhage in children in Thailand. This diagnosis was confirmed by detecting specific antibodies against GNATHOSTOMA SPINIGERUM in serum and CSF by Western blot. Therapy was started with albendazole and dexamethasone and the girl made a complete recovery. In case of intracranial haemorrhage cerebral gnathostomiasis should be considered if the patient originates from an endemic area.</description><identifier>ISSN: 0300-8630</identifier><identifier>EISSN: 1439-3824</identifier><identifier>DOI: 10.1055/s-2003-41401</identifier><identifier>PMID: 12929012</identifier><identifier>CODEN: KLPDB2</identifier><language>eng</language><publisher>Stuttgart: Thieme</publisher><subject>Acute Disease ; Adolescent ; Albendazole - administration & dosage ; Albendazole - therapeutic use ; Animals ; Anthelmintics - administration & dosage ; Anthelmintics - therapeutic use ; Anti-Inflammatory Agents - administration & dosage ; Anti-Inflammatory Agents - therapeutic use ; Antibodies, Helminth - blood ; Antibodies, Helminth - cerebrospinal fluid ; Biological and medical sciences ; Blotting, Western ; Brain Diseases - complications ; Brain Diseases - diagnosis ; Brain Diseases - diagnostic imaging ; Brain Diseases - parasitology ; Cerebral Angiography ; Dexamethasone - administration & dosage ; Dexamethasone - therapeutic use ; Diseases caused by nematodes ; Drug Therapy, Combination ; Female ; Gnathostoma - immunology ; Helminthic diseases ; Humans ; Infectious diseases ; Intracranial Hemorrhages - diagnosis ; Intracranial Hemorrhages - diagnostic imaging ; Intracranial Hemorrhages - etiology ; Larva migrans syndromes ; Medical sciences ; Originalarbeit ; Parasitic diseases ; Paresis - etiology ; Spirurida Infections - complications ; Spirurida Infections - diagnosis ; Spirurida Infections - drug therapy ; Spirurida Infections - immunology ; Time Factors</subject><ispartof>Klinische Pädiatrie, 2003-07, Vol.215 (4), p.223-225</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-38552aefd67e6417d992fd371ce4400fcfa83424ccb12f677e6cc17681915b143</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2003-41401.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/s-2003-41401$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,776,780,3004,27903,27904,54538,54539</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15066519$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12929012$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Germann, R.</creatorcontrib><creatorcontrib>Schächtele, M.</creatorcontrib><creatorcontrib>Neßler, G.</creatorcontrib><creatorcontrib>Seitz, U.</creatorcontrib><creatorcontrib>Kniehl, E.</creatorcontrib><title>Cerebral Gnathostomiasis as a Cause of an Extended Intracranial Bleeding</title><title>Klinische Pädiatrie</title><addtitle>Klin Padiatr</addtitle><description>Abstract
This is a report of a fourteen year old Thai-girl who presented with acute hemiparesis because of intracranial haemorrhage six weeks after immigrating to Germany. Marked blood eosinophilia and raised IgE in serum in comparison with her origin led to the suspected diagnosis of parasitosis. Angiography showed mycotic aneurysm typical for cerebral gnathostomiasis one of the major causes of intracranial haemorrhage in children in Thailand. This diagnosis was confirmed by detecting specific antibodies against GNATHOSTOMA SPINIGERUM in serum and CSF by Western blot. Therapy was started with albendazole and dexamethasone and the girl made a complete recovery. In case of intracranial haemorrhage cerebral gnathostomiasis should be considered if the patient originates from an endemic area.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Albendazole - administration & dosage</subject><subject>Albendazole - therapeutic use</subject><subject>Animals</subject><subject>Anthelmintics - administration & dosage</subject><subject>Anthelmintics - therapeutic use</subject><subject>Anti-Inflammatory Agents - administration & dosage</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Antibodies, Helminth - blood</subject><subject>Antibodies, Helminth - cerebrospinal fluid</subject><subject>Biological and medical sciences</subject><subject>Blotting, Western</subject><subject>Brain Diseases - complications</subject><subject>Brain Diseases - diagnosis</subject><subject>Brain Diseases - diagnostic imaging</subject><subject>Brain Diseases - parasitology</subject><subject>Cerebral Angiography</subject><subject>Dexamethasone - administration & dosage</subject><subject>Dexamethasone - therapeutic use</subject><subject>Diseases caused by nematodes</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Gnathostoma - immunology</subject><subject>Helminthic diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Intracranial Hemorrhages - diagnosis</subject><subject>Intracranial Hemorrhages - diagnostic imaging</subject><subject>Intracranial Hemorrhages - etiology</subject><subject>Larva migrans syndromes</subject><subject>Medical sciences</subject><subject>Originalarbeit</subject><subject>Parasitic diseases</subject><subject>Paresis - etiology</subject><subject>Spirurida Infections - complications</subject><subject>Spirurida Infections - diagnosis</subject><subject>Spirurida Infections - drug therapy</subject><subject>Spirurida Infections - immunology</subject><subject>Time Factors</subject><issn>0300-8630</issn><issn>1439-3824</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0U1LAzEQBuAgiq3Vm2fZi15kdSbJfuSoS20LBS96DtnsrN2yH3WzC_rvTW1FGMjlmTAvL2PXCA8IUfToQg4gQokS8IRNUQoVipTLUzYFARCmsYAJu3BuC4BSgTpnE-SKK0A-ZcuMesp7UweL1gybzg1dUxlXucD4CTIzOgq6MjBtMP8aqC2oCFbt0Bvbm7bya881UVG1H5fsrDS1o6vjO2PvL_O3bBmuXxer7GkdWoHx4C-LIm6oLOKEYolJoRQvC5GgJSkBSluaVEgurc2Rl3HilbWYxCkqjHIfbsbuDv_u-u5zJDfopnKW6tq01I1OJyJKU5GChzdHOOYNFXrXV43pv_Vfdg9uj8A4a-rSB7KV-3cRxHGEyrv7gxs2FTWkt93Ytz6iRtD7BrTT-wb0bwPiB9Fbc7c</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>Germann, R.</creator><creator>Schächtele, M.</creator><creator>Neßler, G.</creator><creator>Seitz, U.</creator><creator>Kniehl, E.</creator><general>Thieme</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>Cerebral Gnathostomiasis as a Cause of an Extended Intracranial Bleeding</title><author>Germann, R. ; Schächtele, M. ; Neßler, G. ; Seitz, U. ; Kniehl, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-38552aefd67e6417d992fd371ce4400fcfa83424ccb12f677e6cc17681915b143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Albendazole - administration & dosage</topic><topic>Albendazole - therapeutic use</topic><topic>Animals</topic><topic>Anthelmintics - administration & dosage</topic><topic>Anthelmintics - therapeutic use</topic><topic>Anti-Inflammatory Agents - administration & dosage</topic><topic>Anti-Inflammatory Agents - therapeutic use</topic><topic>Antibodies, Helminth - blood</topic><topic>Antibodies, Helminth - cerebrospinal fluid</topic><topic>Biological and medical sciences</topic><topic>Blotting, Western</topic><topic>Brain Diseases - complications</topic><topic>Brain Diseases - diagnosis</topic><topic>Brain Diseases - diagnostic imaging</topic><topic>Brain Diseases - parasitology</topic><topic>Cerebral Angiography</topic><topic>Dexamethasone - administration & dosage</topic><topic>Dexamethasone - therapeutic use</topic><topic>Diseases caused by nematodes</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Gnathostoma - immunology</topic><topic>Helminthic diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Intracranial Hemorrhages - diagnosis</topic><topic>Intracranial Hemorrhages - diagnostic imaging</topic><topic>Intracranial Hemorrhages - etiology</topic><topic>Larva migrans syndromes</topic><topic>Medical sciences</topic><topic>Originalarbeit</topic><topic>Parasitic diseases</topic><topic>Paresis - etiology</topic><topic>Spirurida Infections - complications</topic><topic>Spirurida Infections - diagnosis</topic><topic>Spirurida Infections - drug therapy</topic><topic>Spirurida Infections - immunology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Germann, R.</creatorcontrib><creatorcontrib>Schächtele, M.</creatorcontrib><creatorcontrib>Neßler, G.</creatorcontrib><creatorcontrib>Seitz, U.</creatorcontrib><creatorcontrib>Kniehl, E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Klinische Pädiatrie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Germann, R.</au><au>Schächtele, M.</au><au>Neßler, G.</au><au>Seitz, U.</au><au>Kniehl, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral Gnathostomiasis as a Cause of an Extended Intracranial Bleeding</atitle><jtitle>Klinische Pädiatrie</jtitle><addtitle>Klin Padiatr</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>215</volume><issue>4</issue><spage>223</spage><epage>225</epage><pages>223-225</pages><issn>0300-8630</issn><eissn>1439-3824</eissn><coden>KLPDB2</coden><abstract>Abstract
This is a report of a fourteen year old Thai-girl who presented with acute hemiparesis because of intracranial haemorrhage six weeks after immigrating to Germany. Marked blood eosinophilia and raised IgE in serum in comparison with her origin led to the suspected diagnosis of parasitosis. Angiography showed mycotic aneurysm typical for cerebral gnathostomiasis one of the major causes of intracranial haemorrhage in children in Thailand. This diagnosis was confirmed by detecting specific antibodies against GNATHOSTOMA SPINIGERUM in serum and CSF by Western blot. Therapy was started with albendazole and dexamethasone and the girl made a complete recovery. In case of intracranial haemorrhage cerebral gnathostomiasis should be considered if the patient originates from an endemic area.</abstract><cop>Stuttgart</cop><pub>Thieme</pub><pmid>12929012</pmid><doi>10.1055/s-2003-41401</doi><tpages>3</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Thieme Connect Journals |
| subjects | Acute Disease Adolescent Albendazole - administration & dosage Albendazole - therapeutic use Animals Anthelmintics - administration & dosage Anthelmintics - therapeutic use Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - therapeutic use Antibodies, Helminth - blood Antibodies, Helminth - cerebrospinal fluid Biological and medical sciences Blotting, Western Brain Diseases - complications Brain Diseases - diagnosis Brain Diseases - diagnostic imaging Brain Diseases - parasitology Cerebral Angiography Dexamethasone - administration & dosage Dexamethasone - therapeutic use Diseases caused by nematodes Drug Therapy, Combination Female Gnathostoma - immunology Helminthic diseases Humans Infectious diseases Intracranial Hemorrhages - diagnosis Intracranial Hemorrhages - diagnostic imaging Intracranial Hemorrhages - etiology Larva migrans syndromes Medical sciences Originalarbeit Parasitic diseases Paresis - etiology Spirurida Infections - complications Spirurida Infections - diagnosis Spirurida Infections - drug therapy Spirurida Infections - immunology Time Factors |
| title | Cerebral Gnathostomiasis as a Cause of an Extended Intracranial Bleeding |
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