Synthesis and Characterization of Thermoreversible Biopolymer Microgels Based on Hydrogen Bonded Nucleobase Pairing

We describe the synthesis and characterization of a thermoreversibly cross-linked biopolymer microgel based on protein, DNA, and peptide nucleic acid (PNA) components. The DNA assembles into a trifunctional three-way junction (TWJ) with single-stranded overhangs. PNA oligomers complementary to these...

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Veröffentlicht in:	Journal of the American Chemical Society 2003-08, Vol.125 (34), p.10250-10256
Hauptverfasser:	Cao, Rong, Gu, Zhenyu, Hsu, Lorraine, Patterson, Gary D, Armitage, Bruce A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Avidin - chemistry Base Sequence Biological and medical sciences Biotin - chemistry DNA - chemical synthesis DNA - chemistry Fundamental and applied biological sciences. Psychology Gels General aspects, investigation methods Hot Temperature Hydrogen Bonding Light Molecular Sequence Data Nucleic Acid Conformation Nucleic Acid Hybridization Nucleic acids Oligonucleotides - chemical synthesis Oligonucleotides - chemistry Peptide Nucleic Acids - chemical synthesis Peptide Nucleic Acids - chemistry Proteins - chemical synthesis Proteins - chemistry Scattering, Radiation
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