Sub-Femtomole Peptide Detection in Ion Mobility-Time-of-Flight Mass Spectrometry Measurements

Sensitivity and detection limit enhancements are obtained for peptides by performing high repetition rate (150 Hz) matrix-assisted laser desorption/ionization (MALDI) coupled with ion mobility-time-of-flight mass spectrometry. Absolute limits of detection (3σ) for model peptides are on the order of...

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Veröffentlicht in:	Journal of proteome research 2003-07, Vol.2 (4), p.427-430
Hauptverfasser:	McLean, John A, Russell, David H
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin I - analysis Angiotensin II - analysis Animals Cattle Hemoglobins - chemistry Humans Peptide Fragments - analysis Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
Online-Zugang:	Volltext
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