The dorsal column pathway facilitates visceromotor responses to colorectal distention after colon inflammation in rats

Recent clinical studies have demonstrated that a midline lesion of the dorsal columns (DC, limited midline myelotomy) reduces pain of visceral origin in patients with pelvic cancer. Animal experiments showed that a DC lesion leads to decreased activation of thalamic neurons by visceral stimuli, lowe...

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Veröffentlicht in:	Pain (Amsterdam) 2003-08, Vol.104 (3), p.501-507
Hauptverfasser:	Palecek, J, Willis, W.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Catheterization Colitis - physiopathology Colon - innervation Colon - pathology Colon - physiopathology Colon inflammation Dorsal columns Electromyography - methods Fundamental and applied biological sciences. Psychology Male Midline myelotomy Posterior Horn Cells - physiology Rats Rats, Sprague-Dawley Rectum - innervation Rectum - pathology Rectum - physiopathology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Ventral Thalamic Nuclei Vertebrates: nervous system and sense organs Visceral hyperalgesia Visceral pain
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