Interferon-stimulated gene expression and hepatitis C viral dynamics during different interferon regimens

Background/Aims: To address the molecular mechanism for enhanced antiviral efficacy associated with a frequent dosing of interferon (IFN)-beta. Methods: Serum hepatitis C viral (HCV) dynamics, double-stranded RNA-activated protein kinase (PKR) mRNA and MxA mRNA levels in peripheral blood mononuclear...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of hepatology 2003-09, Vol.39 (3), p.421-427
Hauptverfasser:	Asahina, Yasuhiro, Izumi, Namiki, Uchihara, Masakatsu, Noguchi, Osamu, Nishimura, Yuki, Inoue, Kazunari, Ueda, Ken, Tsuchiya, Kaoru, Hamano, Kosei, Itakura, Jun, Miyake, Shozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antiviral Agents - administration & dosage Biological and medical sciences Double-stranded RNA-activated protein kinase (PKR) Drug Administration Schedule eIF-2 Kinase - genetics Female Gastroenterology. Liver. Pancreas. Abdomen Gene Expression - drug effects GTP-Binding Proteins - genetics Hepacivirus - drug effects Hepatitis C - drug therapy Hepatitis C - metabolism Human viral diseases Humans Infectious diseases Interferon-beta Interferon-beta - administration & dosage Intracellular Membranes - metabolism Liver - metabolism Male Medical sciences Middle Aged Monocytes - metabolism MxA Myxovirus Resistance Proteins Peripheral blood mononuclear cell Real-time detection PCR RNA, Messenger - blood Viral diseases Viral hepatitis Viral kinetics Viral Load
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!