Pasteurella multocida- and Pasteurella haemolytica-ghosts: new vaccine candidates

Pasteurella multocida is an important animal pathogen. Bacterial ghosts produced by the expression of phage PhiX174 lysis gene E are empty cells devoid of cytoplasmic and genomic material. Lysis of P. multocida 7A and P. haemolytica A1 carrying Pasteurella-specific lysis vectors (pSR2 and pSON2) occ...

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Veröffentlicht in:	Vaccine 2003-09, Vol.21 (25-26), p.3988-3997
Hauptverfasser:	Marchart, J., Dropmann, G., Lechleitner, S., Schlapp, T., Wanner, G., Szostak, M.P., Lubitz, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antigens Bacterial ghost Bacterial Vaccines - immunology Bacteriophage phi X 174 - genetics Blotting, Western Deoxyribonucleic acid DNA DNA, Bacterial - genetics DNA, Recombinant - genetics Dose-Response Relationship, Immunologic E coli Electrophoresis, Polyacrylamide Gel Expression vectors Gene expression Ghosts Homology Immunization Immunoglobulins Lysis Mannheimia haemolytica - immunology Mannheimia haemolytica - ultrastructure Mannheimia haemolytica - virology Mice Microscopy, Electron, Scanning Pasteurella Pasteurella multocida Pasteurella multocida - immunology Pasteurella multocida - ultrastructure Pasteurella multocida - virology Phages Plasmids Plasmids - genetics Protection Proteins Rabbits Salmonella Temperature Transformation, Bacterial Vaccine Vaccines
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