Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: A potential explanation for the blood-transfusion effect

Preoperative blood transfusion has had a significant historic impact on graft outcome in clinical kidney transplantation, and the effect has been widely replicated in many experimental transplant models. Although the mechanisms underlying the blood-transfusion effect are poorly understood, one possi...

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Veröffentlicht in:	Transplantation 2003-08, Vol.76 (3), p.449-455
Hauptverfasser:	BUSHELL, Andrew, KARIM, Mahzuz, KINGSLEY, Cherry I, WOOD, Kathryn J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Transfusion CD4-Positive T-Lymphocytes - immunology Graft Survival - immunology Isoantigens - immunology Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred CBA Receptors, Interleukin-2 - analysis Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Transplantation Immunology
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