Caffeine increases spinal excitability in humans

The Hoffman reflex (H reflex) has long been established as a measure of spinal excitability. Caffeine is one of the most widely consumed drugs in the world. Because it is known to increase excitatory neurotransmission, we hypothesized that caffeine would increase spinal excitability and thus alter t...

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Veröffentlicht in:	Muscle & nerve 2003-09, Vol.28 (3), p.359-364
Hauptverfasser:	Walton, C., Kalmar, J., Cafarelli, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - physiology Adult Biological and medical sciences caffeine Caffeine - pharmacology Central Nervous System Stimulants - pharmacology Electric Stimulation Electromyography - drug effects Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Fundamental and applied biological sciences. Psychology H-reflex H-Reflex - drug effects H-Reflex - physiology Humans Male Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Muscle Contraction - drug effects Muscle Contraction - physiology Neurons - drug effects Neurons - physiology recruitment curve soleus Spinal Cord - drug effects Spinal Cord - physiology spinal excitability Synaptic Transmission - drug effects Synaptic Transmission - physiology Up-Regulation - drug effects Up-Regulation - physiology Vertebrates: nervous system and sense organs
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