Heparan Sulfate 6-O-Sulfotransferase Is Essential for Muscle Development in Zebrafish

Heparan sulfate proteoglycans function in development and disease. They consist of a core protein with attached heparan sulfate chains that are altered by a series of carbohydrate-modifying enzymes and sulfotransferases. Here, we report on the identification and characterization of a gene encoding z...

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Veröffentlicht in:	The Journal of biological chemistry 2003-08, Vol.278 (33), p.31118-31127
Hauptverfasser:	Bink, Robert J., Habuchi, Hiroko, Lele, Zsolt, Dolk, Edward, Joore, Jos, Rauch, Gerd-Jörg, Geisler, Robert, Wilson, Stephen W., den Hertog, Jeroen, Kimata, Koji, Zivkovic, Danica
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Differentiation Danio rerio Freshwater Fugu rubripes Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic heparan sulfate 6-O-sulfotransferase Heparan Sulfate Proteoglycans - metabolism hs6st gene Molecular Sequence Data Muscle, Skeletal - cytology Muscle, Skeletal - embryology Muscle, Skeletal - enzymology Oligonucleotides, Antisense - pharmacology Phenotype proteoglycans Somites - enzymology Sulfotransferases - genetics Sulfotransferases - metabolism Zebrafish - genetics
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