The prolactin response to intravenous dextroamphetamine in normal young men and postmenopausal women
D-amphetamine was administered intravenously in doses of 0.1 mg/kg and 0.15 mg/kg to normal young men and postmenopausal women in both morning and evening. No suppression of PRL secretion after amphetamine was found, and, in the postmenopausal women, no significant change in PRL levels in any dose o...
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| Veröffentlicht in: | Life sciences (1973) 1981-05, Vol.28 (21), p.2337-2342 |
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| container_end_page | 2342 |
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| container_issue | 21 |
| container_start_page | 2337 |
| container_title | Life sciences (1973) |
| container_volume | 28 |
| creator | Halbreich, Uriel Sachar, Edward J. Asnis, Gregory M. Swami Nathan, R. Halpern, Frieda S. |
| description | D-amphetamine was administered intravenously in doses of 0.1 mg/kg and 0.15 mg/kg to normal young men and postmenopausal women in both morning and evening. No suppression of PRL secretion after amphetamine was found, and, in the postmenopausal women, no significant change in PRL levels in any dose or time condition occured. However, a significant and relatively consistent PRL release was induced in the young men in the evening by the higher dose. This latter response suggests that, in humans, dextroamphetamine can actually stimulate prolactin perhaps by a mechanism other than alteration in dopaminergic tone. |
| doi_str_mv | 10.1016/0024-3205(81)90497-5 |
| format | Article |
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No suppression of PRL secretion after amphetamine was found, and, in the postmenopausal women, no significant change in PRL levels in any dose or time condition occured. However, a significant and relatively consistent PRL release was induced in the young men in the evening by the higher dose. This latter response suggests that, in humans, dextroamphetamine can actually stimulate prolactin perhaps by a mechanism other than alteration in dopaminergic tone.</description><identifier>ISSN: 0024-3205</identifier><identifier>EISSN: 1879-0631</identifier><identifier>DOI: 10.1016/0024-3205(81)90497-5</identifier><identifier>PMID: 7253823</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adult ; Dextroamphetamine - administration & dosage ; Dextroamphetamine - pharmacology ; Female ; Humans ; Injections, Intravenous ; Male ; Menopause ; Middle Aged ; Prolactin - blood ; Sex Factors ; Time Factors</subject><ispartof>Life sciences (1973), 1981-05, Vol.28 (21), p.2337-2342</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c272t-90c6a2059dd3e58008a1b69ca50512d277b6f0cc36c2bb78bff8c54fd4a9a46e3</citedby><cites>FETCH-LOGICAL-c272t-90c6a2059dd3e58008a1b69ca50512d277b6f0cc36c2bb78bff8c54fd4a9a46e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0024-3205(81)90497-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7253823$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Halbreich, Uriel</creatorcontrib><creatorcontrib>Sachar, Edward J.</creatorcontrib><creatorcontrib>Asnis, Gregory M.</creatorcontrib><creatorcontrib>Swami Nathan, R.</creatorcontrib><creatorcontrib>Halpern, Frieda S.</creatorcontrib><title>The prolactin response to intravenous dextroamphetamine in normal young men and postmenopausal women</title><title>Life sciences (1973)</title><addtitle>Life Sci</addtitle><description>D-amphetamine was administered intravenously in doses of 0.1 mg/kg and 0.15 mg/kg to normal young men and postmenopausal women in both morning and evening. No suppression of PRL secretion after amphetamine was found, and, in the postmenopausal women, no significant change in PRL levels in any dose or time condition occured. However, a significant and relatively consistent PRL release was induced in the young men in the evening by the higher dose. This latter response suggests that, in humans, dextroamphetamine can actually stimulate prolactin perhaps by a mechanism other than alteration in dopaminergic tone.</description><subject>Adult</subject><subject>Dextroamphetamine - administration & dosage</subject><subject>Dextroamphetamine - pharmacology</subject><subject>Female</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Male</subject><subject>Menopause</subject><subject>Middle Aged</subject><subject>Prolactin - blood</subject><subject>Sex Factors</subject><subject>Time Factors</subject><issn>0024-3205</issn><issn>1879-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtP3TAQha2qFVyg_wAkrypYBPyIY2dTCaE-kJC6gbXl2JNilNip7VD49_j2XrHsajw6Z2Z8PoROKbmkhHZXhLC24YyIc0UvetL2shEf0IYq2Tek4_Qj2rxbDtFRzk-EECEkP0AHkgmuGN8gd_8IeElxMrb4gBPkJYYMuETsQ0nmGUJcM3bwUlI08_IIxcw-QFVxiGk2E36Na_iNZwjYBIeXmEt9x8WsuYp_Y21O0KfRTBk-7-sxevj-7f7mZ3P368ftzfVdY5lkpemJ7Uz9bO8cB6EIUYYOXW-NIIIyx6QcupFYyzvLhkGqYRyVFe3oWtObtgN-jL7s9tZAf1bIRc8-W5gmE6Cm0JKLtleqq8Z2Z7Qp5pxg1Evys0mvmhK9hau35PSWnFZU_4OrRR072-9fhxnc-9CeZtW_7nSoIZ89JJ2th2DB-QS2aBf9_w-8AZHqizc</recordid><startdate>19810521</startdate><enddate>19810521</enddate><creator>Halbreich, Uriel</creator><creator>Sachar, Edward J.</creator><creator>Asnis, Gregory M.</creator><creator>Swami Nathan, R.</creator><creator>Halpern, Frieda S.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19810521</creationdate><title>The prolactin response to intravenous dextroamphetamine in normal young men and postmenopausal women</title><author>Halbreich, Uriel ; Sachar, Edward J. ; Asnis, Gregory M. ; Swami Nathan, R. ; Halpern, Frieda S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-90c6a2059dd3e58008a1b69ca50512d277b6f0cc36c2bb78bff8c54fd4a9a46e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adult</topic><topic>Dextroamphetamine - administration & dosage</topic><topic>Dextroamphetamine - pharmacology</topic><topic>Female</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Male</topic><topic>Menopause</topic><topic>Middle Aged</topic><topic>Prolactin - blood</topic><topic>Sex Factors</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Halbreich, Uriel</creatorcontrib><creatorcontrib>Sachar, Edward J.</creatorcontrib><creatorcontrib>Asnis, Gregory M.</creatorcontrib><creatorcontrib>Swami Nathan, R.</creatorcontrib><creatorcontrib>Halpern, Frieda S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Life sciences (1973)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Halbreich, Uriel</au><au>Sachar, Edward J.</au><au>Asnis, Gregory M.</au><au>Swami Nathan, R.</au><au>Halpern, Frieda S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prolactin response to intravenous dextroamphetamine in normal young men and postmenopausal women</atitle><jtitle>Life sciences (1973)</jtitle><addtitle>Life Sci</addtitle><date>1981-05-21</date><risdate>1981</risdate><volume>28</volume><issue>21</issue><spage>2337</spage><epage>2342</epage><pages>2337-2342</pages><issn>0024-3205</issn><eissn>1879-0631</eissn><abstract>D-amphetamine was administered intravenously in doses of 0.1 mg/kg and 0.15 mg/kg to normal young men and postmenopausal women in both morning and evening. No suppression of PRL secretion after amphetamine was found, and, in the postmenopausal women, no significant change in PRL levels in any dose or time condition occured. However, a significant and relatively consistent PRL release was induced in the young men in the evening by the higher dose. This latter response suggests that, in humans, dextroamphetamine can actually stimulate prolactin perhaps by a mechanism other than alteration in dopaminergic tone.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>7253823</pmid><doi>10.1016/0024-3205(81)90497-5</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0024-3205 |
| ispartof | Life sciences (1973), 1981-05, Vol.28 (21), p.2337-2342 |
| issn | 0024-3205 1879-0631 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Dextroamphetamine - administration & dosage Dextroamphetamine - pharmacology Female Humans Injections, Intravenous Male Menopause Middle Aged Prolactin - blood Sex Factors Time Factors |
| title | The prolactin response to intravenous dextroamphetamine in normal young men and postmenopausal women |
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