Effects of pseudoephedrine on maximal cycling power and submaximal cycling efficiency
To study the effects of a therapeutic dose of pseudoephedrine on anaerobic cycling power and aerobic cycling efficiency. Eleven healthy moderately trained males (VO (2peak) 4.4 +/- 0.8 L x min(-1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic...
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| Veröffentlicht in: | Medicine and science in sports and exercise 2003-08, Vol.35 (8), p.1316-1319 |
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| container_title | Medicine and science in sports and exercise |
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| creator | HODGES, Alastair N. H LYNN, Brenna M BULA, Jonathan E DONALDSON, Meghan G DAGENAIS, Marc O MCKENZIE, Donald C |
| description | To study the effects of a therapeutic dose of pseudoephedrine on anaerobic cycling power and aerobic cycling efficiency.
Eleven healthy moderately trained males (VO (2peak) 4.4 +/- 0.8 L x min(-1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic (Wingate test) and aerobic (VO (2peak) test) cycling power. Subjects ingested either 60 mg of pseudoephedrine hydrochloride (D) or a placebo (P) and, after 90 min of rest, a Wingate and a cycling efficiency test were performed. During the cycling efficiency test, heart rate (HR) and VO(2) were averaged for the last 5 min of a 10-min cycle at 40% and 60% of the peak power achieved during the VO (2peak) test.
There were no significant differences in peak power (B = 860 +/- 154, D = 926 +/- 124, P = 908 +/- 118 W), total work (B = 20 +/- 3, D = 21 +/- 3, P = 21 +/- 3 kJ), or fatigue index (B = 39 +/- 8, D = 45 +/- 5, P = 43 +/- 5%). There were no significant differences in HR at 40% power (D = 138 +/- 10, P = 137 +/- 10 beats.min-1) or 60% power (D = 161 +/- 11, P = 160 +/- 11 beats x min(-1). There were no significant differences in cycling efficiency at 40% power (D = 18.8 +/- 1.8, P = 18.5 +/- 1.8%) or 60% power (D = 20.3 +/- 2.0, P = 20.1 +/- 2.1%).
A therapeutic dose of pseudoephedrine hydrochloride does not affect anaerobic cycling performance or aerobic cycling efficiency. |
| doi_str_mv | 10.1249/01.MSS.0000078925.30346.F8 |
| format | Article |
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Eleven healthy moderately trained males (VO (2peak) 4.4 +/- 0.8 L x min(-1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic (Wingate test) and aerobic (VO (2peak) test) cycling power. Subjects ingested either 60 mg of pseudoephedrine hydrochloride (D) or a placebo (P) and, after 90 min of rest, a Wingate and a cycling efficiency test were performed. During the cycling efficiency test, heart rate (HR) and VO(2) were averaged for the last 5 min of a 10-min cycle at 40% and 60% of the peak power achieved during the VO (2peak) test.
There were no significant differences in peak power (B = 860 +/- 154, D = 926 +/- 124, P = 908 +/- 118 W), total work (B = 20 +/- 3, D = 21 +/- 3, P = 21 +/- 3 kJ), or fatigue index (B = 39 +/- 8, D = 45 +/- 5, P = 43 +/- 5%). There were no significant differences in HR at 40% power (D = 138 +/- 10, P = 137 +/- 10 beats.min-1) or 60% power (D = 161 +/- 11, P = 160 +/- 11 beats x min(-1). There were no significant differences in cycling efficiency at 40% power (D = 18.8 +/- 1.8, P = 18.5 +/- 1.8%) or 60% power (D = 20.3 +/- 2.0, P = 20.1 +/- 2.1%).
A therapeutic dose of pseudoephedrine hydrochloride does not affect anaerobic cycling performance or aerobic cycling efficiency.</description><identifier>ISSN: 0195-9131</identifier><identifier>EISSN: 1530-0315</identifier><identifier>DOI: 10.1249/01.MSS.0000078925.30346.F8</identifier><identifier>PMID: 12900684</identifier><identifier>CODEN: MSPEDA</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Bicycling - physiology ; Biological and medical sciences ; Catecholaminergic system ; Cross-Over Studies ; Double-Blind Method ; Energy Metabolism - drug effects ; Ephedrine - administration & dosage ; Exercise - physiology ; Humans ; Male ; Medical sciences ; Muscle, Skeletal - drug effects ; Neuropharmacology ; Neurotransmitters. Neurotransmission. Receptors ; Oxygen Consumption - drug effects ; Pharmacology. Drug treatments ; Physical Endurance - drug effects ; Space life sciences ; Task Performance and Analysis</subject><ispartof>Medicine and science in sports and exercise, 2003-08, Vol.35 (8), p.1316-1319</ispartof><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-c183c11faf845db522d1583a2de6f8c413ed3b4dba25996e90832336557701783</citedby><cites>FETCH-LOGICAL-c428t-c183c11faf845db522d1583a2de6f8c413ed3b4dba25996e90832336557701783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15015877$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12900684$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HODGES, Alastair N. H</creatorcontrib><creatorcontrib>LYNN, Brenna M</creatorcontrib><creatorcontrib>BULA, Jonathan E</creatorcontrib><creatorcontrib>DONALDSON, Meghan G</creatorcontrib><creatorcontrib>DAGENAIS, Marc O</creatorcontrib><creatorcontrib>MCKENZIE, Donald C</creatorcontrib><title>Effects of pseudoephedrine on maximal cycling power and submaximal cycling efficiency</title><title>Medicine and science in sports and exercise</title><addtitle>Med Sci Sports Exerc</addtitle><description>To study the effects of a therapeutic dose of pseudoephedrine on anaerobic cycling power and aerobic cycling efficiency.
Eleven healthy moderately trained males (VO (2peak) 4.4 +/- 0.8 L x min(-1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic (Wingate test) and aerobic (VO (2peak) test) cycling power. Subjects ingested either 60 mg of pseudoephedrine hydrochloride (D) or a placebo (P) and, after 90 min of rest, a Wingate and a cycling efficiency test were performed. During the cycling efficiency test, heart rate (HR) and VO(2) were averaged for the last 5 min of a 10-min cycle at 40% and 60% of the peak power achieved during the VO (2peak) test.
There were no significant differences in peak power (B = 860 +/- 154, D = 926 +/- 124, P = 908 +/- 118 W), total work (B = 20 +/- 3, D = 21 +/- 3, P = 21 +/- 3 kJ), or fatigue index (B = 39 +/- 8, D = 45 +/- 5, P = 43 +/- 5%). There were no significant differences in HR at 40% power (D = 138 +/- 10, P = 137 +/- 10 beats.min-1) or 60% power (D = 161 +/- 11, P = 160 +/- 11 beats x min(-1). There were no significant differences in cycling efficiency at 40% power (D = 18.8 +/- 1.8, P = 18.5 +/- 1.8%) or 60% power (D = 20.3 +/- 2.0, P = 20.1 +/- 2.1%).
A therapeutic dose of pseudoephedrine hydrochloride does not affect anaerobic cycling performance or aerobic cycling efficiency.</description><subject>Adult</subject><subject>Bicycling - physiology</subject><subject>Biological and medical sciences</subject><subject>Catecholaminergic system</subject><subject>Cross-Over Studies</subject><subject>Double-Blind Method</subject><subject>Energy Metabolism - drug effects</subject><subject>Ephedrine - administration & dosage</subject><subject>Exercise - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle, Skeletal - drug effects</subject><subject>Neuropharmacology</subject><subject>Neurotransmitters. Neurotransmission. Receptors</subject><subject>Oxygen Consumption - drug effects</subject><subject>Pharmacology. Drug treatments</subject><subject>Physical Endurance - drug effects</subject><subject>Space life sciences</subject><subject>Task Performance and Analysis</subject><issn>0195-9131</issn><issn>1530-0315</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAQgC0EouXxF1CEBFuCz2cnDhtCFJBADNDZcu0zBKVJiFtB_z0pVKrEwi033Hevj7FT4BkIWV5wyB6fnzO-jkKXQmXIUebZRO-wMSjkKUdQu2zMoVRpCQgjdhDj-xpHhH02AlFynms5ZtObEMgtYtKGpIu09C11b-T7qqGkbZK5_armtk7cytVV85p07Sf1iW18Epezv0UKoXIVNW51xPaCrSMdb_Ihm05uXq7v0oen2_vrq4fUSaEXqQONDiDYoKXyMyWEB6XRCk950E4CkseZ9DMrVFnmVHKNAjFXqig4FBoP2fnv3K5vP5YUF2ZeRUd1bRtql9EUqKQe2H9B0JrLQsAAXv6Crm9j7CmYrh-e7FcGuFnbNxzMYN9s7Zsf-2ayPudks2WQQ37butE9AGcbwEZn69DbxlVxyyk-_F8U-A1dSo2Y</recordid><startdate>20030801</startdate><enddate>20030801</enddate><creator>HODGES, Alastair N. H</creator><creator>LYNN, Brenna M</creator><creator>BULA, Jonathan E</creator><creator>DONALDSON, Meghan G</creator><creator>DAGENAIS, Marc O</creator><creator>MCKENZIE, Donald C</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>20030801</creationdate><title>Effects of pseudoephedrine on maximal cycling power and submaximal cycling efficiency</title><author>HODGES, Alastair N. H ; LYNN, Brenna M ; BULA, Jonathan E ; DONALDSON, Meghan G ; DAGENAIS, Marc O ; MCKENZIE, Donald C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-c183c11faf845db522d1583a2de6f8c413ed3b4dba25996e90832336557701783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Bicycling - physiology</topic><topic>Biological and medical sciences</topic><topic>Catecholaminergic system</topic><topic>Cross-Over Studies</topic><topic>Double-Blind Method</topic><topic>Energy Metabolism - drug effects</topic><topic>Ephedrine - administration & dosage</topic><topic>Exercise - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscle, Skeletal - drug effects</topic><topic>Neuropharmacology</topic><topic>Neurotransmitters. Neurotransmission. Receptors</topic><topic>Oxygen Consumption - drug effects</topic><topic>Pharmacology. Drug treatments</topic><topic>Physical Endurance - drug effects</topic><topic>Space life sciences</topic><topic>Task Performance and Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HODGES, Alastair N. H</creatorcontrib><creatorcontrib>LYNN, Brenna M</creatorcontrib><creatorcontrib>BULA, Jonathan E</creatorcontrib><creatorcontrib>DONALDSON, Meghan G</creatorcontrib><creatorcontrib>DAGENAIS, Marc O</creatorcontrib><creatorcontrib>MCKENZIE, Donald C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Medicine and science in sports and exercise</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HODGES, Alastair N. H</au><au>LYNN, Brenna M</au><au>BULA, Jonathan E</au><au>DONALDSON, Meghan G</au><au>DAGENAIS, Marc O</au><au>MCKENZIE, Donald C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of pseudoephedrine on maximal cycling power and submaximal cycling efficiency</atitle><jtitle>Medicine and science in sports and exercise</jtitle><addtitle>Med Sci Sports Exerc</addtitle><date>2003-08-01</date><risdate>2003</risdate><volume>35</volume><issue>8</issue><spage>1316</spage><epage>1319</epage><pages>1316-1319</pages><issn>0195-9131</issn><eissn>1530-0315</eissn><coden>MSPEDA</coden><abstract>To study the effects of a therapeutic dose of pseudoephedrine on anaerobic cycling power and aerobic cycling efficiency.
Eleven healthy moderately trained males (VO (2peak) 4.4 +/- 0.8 L x min(-1) participated in a double-blinded crossover design. Subjects underwent baseline (B) tests for anaerobic (Wingate test) and aerobic (VO (2peak) test) cycling power. Subjects ingested either 60 mg of pseudoephedrine hydrochloride (D) or a placebo (P) and, after 90 min of rest, a Wingate and a cycling efficiency test were performed. During the cycling efficiency test, heart rate (HR) and VO(2) were averaged for the last 5 min of a 10-min cycle at 40% and 60% of the peak power achieved during the VO (2peak) test.
There were no significant differences in peak power (B = 860 +/- 154, D = 926 +/- 124, P = 908 +/- 118 W), total work (B = 20 +/- 3, D = 21 +/- 3, P = 21 +/- 3 kJ), or fatigue index (B = 39 +/- 8, D = 45 +/- 5, P = 43 +/- 5%). There were no significant differences in HR at 40% power (D = 138 +/- 10, P = 137 +/- 10 beats.min-1) or 60% power (D = 161 +/- 11, P = 160 +/- 11 beats x min(-1). There were no significant differences in cycling efficiency at 40% power (D = 18.8 +/- 1.8, P = 18.5 +/- 1.8%) or 60% power (D = 20.3 +/- 2.0, P = 20.1 +/- 2.1%).
A therapeutic dose of pseudoephedrine hydrochloride does not affect anaerobic cycling performance or aerobic cycling efficiency.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>12900684</pmid><doi>10.1249/01.MSS.0000078925.30346.F8</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0195-9131 |
| ispartof | Medicine and science in sports and exercise, 2003-08, Vol.35 (8), p.1316-1319 |
| issn | 0195-9131 1530-0315 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73548770 |
| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Complete |
| subjects | Adult Bicycling - physiology Biological and medical sciences Catecholaminergic system Cross-Over Studies Double-Blind Method Energy Metabolism - drug effects Ephedrine - administration & dosage Exercise - physiology Humans Male Medical sciences Muscle, Skeletal - drug effects Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Oxygen Consumption - drug effects Pharmacology. Drug treatments Physical Endurance - drug effects Space life sciences Task Performance and Analysis |
| title | Effects of pseudoephedrine on maximal cycling power and submaximal cycling efficiency |
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