Causes of death in patients with non‐Hodgkin's lYMPHOMA
The causes of death and postmortem findings in patients treated for non‐Hodgkin's lymphoma at a single institution over a 13‐year period were reviewed. Postmortem examination (70% of the entire sample) revealed evidence of lymphoma in 67 of 80 patients. The most frequent extranodal sites of inv...
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| Veröffentlicht in: | Cancer 1981-08, Vol.48 (3), p.779-782 |
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| container_title | Cancer |
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| creator | Ostrow, Stanley Diggs, Charles H. Sutherland, John Wiernik, Peter H. |
| description | The causes of death and postmortem findings in patients treated for non‐Hodgkin's lymphoma at a single institution over a 13‐year period were reviewed. Postmortem examination (70% of the entire sample) revealed evidence of lymphoma in 67 of 80 patients. The most frequent extranodal sites of involvement were the respiratory tract, bone marrow, liver, kidney, and gastrointestinal tract in that order. The most common cause of death was infection (33% of cases). Predisposing factors for infection included the underlying disease, (i.e., lymphomatous infiltration of organ systems) and granulocytopenia secondary to combination chemotherapy. Other causes of death included hemorrhage and respiratory failure secondary to lymphomatous infiltration of the lung. Despite advances in therapy and supportive care of patients with non‐Hodgkin's lymphoma, many patients still die of this disease or of sequelae related to its treatment. |
| doi_str_mv | 10.1002/1097-0142(19810801)48:3<779::AID-CNCR2820480320>3.0.CO;2-3 |
| format | Article |
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Postmortem examination (70% of the entire sample) revealed evidence of lymphoma in 67 of 80 patients. The most frequent extranodal sites of involvement were the respiratory tract, bone marrow, liver, kidney, and gastrointestinal tract in that order. The most common cause of death was infection (33% of cases). Predisposing factors for infection included the underlying disease, (i.e., lymphomatous infiltration of organ systems) and granulocytopenia secondary to combination chemotherapy. Other causes of death included hemorrhage and respiratory failure secondary to lymphomatous infiltration of the lung. 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Postmortem examination (70% of the entire sample) revealed evidence of lymphoma in 67 of 80 patients. The most frequent extranodal sites of involvement were the respiratory tract, bone marrow, liver, kidney, and gastrointestinal tract in that order. The most common cause of death was infection (33% of cases). Predisposing factors for infection included the underlying disease, (i.e., lymphomatous infiltration of organ systems) and granulocytopenia secondary to combination chemotherapy. Other causes of death included hemorrhage and respiratory failure secondary to lymphomatous infiltration of the lung. Despite advances in therapy and supportive care of patients with non‐Hodgkin's lymphoma, many patients still die of this disease or of sequelae related to its treatment.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Child</subject><subject>Female</subject><subject>Hemorrhage - complications</subject><subject>Hemorrhage - mortality</subject><subject>Humans</subject><subject>Lymphoma - complications</subject><subject>Lymphoma - drug therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mycoses - complications</subject><subject>Mycoses - mortality</subject><subject>Pneumonia - complications</subject><subject>Pneumonia - mortality</subject><subject>Prognosis</subject><subject>Respiratory Insufficiency - complications</subject><subject>Respiratory Insufficiency - mortality</subject><subject>Sepsis - complications</subject><subject>Sepsis - mortality</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkNtu00AQhlcVqITSR6jkKw4XDrMn725ASMEcUqltqgqkws1obY_BxbGDN1HVOx6BZ-RJ2CihElwg9Wo088_8_-hj7DWHMQcQzzk4kwJX4il3loMF_kzZiXxpjJtMpsdv0vwsvxBWgLIgBbySYxjn8xcilXtsdHt8j40AwKZaycsH7GEIV7E1Qst9tm-Esg7UiLncrwOFpK-Tivzqa9J0ydKvGupWIblu4qDru18_fs766su3pnsSkvbT6flsfjp9xO7Xvg10uKsH7OO7tx_yWXoyf3-cT0_SUmUZpGRUVYui4q7ktZNGe2OVdE6SlR64jiXjuihAZxVlSmpVAxUkOInSam_lAXu89V0O_fc1hRUumlBS2_qO-nVAE0-yTGdx8fN2sRz6EAaqcTk0Cz_cIAfccMUNGtygwT9cUVmUGLkiRq74N9eoAOZzFCij-dHui3WxoOrWegcy6rTVr5uWbu6U_N_gfxT5G-Jnk1Q</recordid><startdate>19810801</startdate><enddate>19810801</enddate><creator>Ostrow, Stanley</creator><creator>Diggs, Charles H.</creator><creator>Sutherland, John</creator><creator>Wiernik, Peter H.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19810801</creationdate><title>Causes of death in patients with non‐Hodgkin's lYMPHOMA</title><author>Ostrow, Stanley ; Diggs, Charles H. ; Sutherland, John ; Wiernik, Peter H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4660-e74df2bd19c1f9375a7843993e83a015e83615bb056de64354f0ebe21e2c85a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Child</topic><topic>Female</topic><topic>Hemorrhage - complications</topic><topic>Hemorrhage - mortality</topic><topic>Humans</topic><topic>Lymphoma - complications</topic><topic>Lymphoma - drug therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mycoses - complications</topic><topic>Mycoses - mortality</topic><topic>Pneumonia - complications</topic><topic>Pneumonia - mortality</topic><topic>Prognosis</topic><topic>Respiratory Insufficiency - complications</topic><topic>Respiratory Insufficiency - mortality</topic><topic>Sepsis - complications</topic><topic>Sepsis - mortality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ostrow, Stanley</creatorcontrib><creatorcontrib>Diggs, Charles H.</creatorcontrib><creatorcontrib>Sutherland, John</creatorcontrib><creatorcontrib>Wiernik, Peter H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ostrow, Stanley</au><au>Diggs, Charles H.</au><au>Sutherland, John</au><au>Wiernik, Peter H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Causes of death in patients with non‐Hodgkin's lYMPHOMA</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1981-08-01</date><risdate>1981</risdate><volume>48</volume><issue>3</issue><spage>779</spage><epage>782</epage><pages>779-782</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>The causes of death and postmortem findings in patients treated for non‐Hodgkin's lymphoma at a single institution over a 13‐year period were reviewed. Postmortem examination (70% of the entire sample) revealed evidence of lymphoma in 67 of 80 patients. The most frequent extranodal sites of involvement were the respiratory tract, bone marrow, liver, kidney, and gastrointestinal tract in that order. The most common cause of death was infection (33% of cases). Predisposing factors for infection included the underlying disease, (i.e., lymphomatous infiltration of organ systems) and granulocytopenia secondary to combination chemotherapy. Other causes of death included hemorrhage and respiratory failure secondary to lymphomatous infiltration of the lung. 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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Child Female Hemorrhage - complications Hemorrhage - mortality Humans Lymphoma - complications Lymphoma - drug therapy Male Middle Aged Mycoses - complications Mycoses - mortality Pneumonia - complications Pneumonia - mortality Prognosis Respiratory Insufficiency - complications Respiratory Insufficiency - mortality Sepsis - complications Sepsis - mortality |
| title | Causes of death in patients with non‐Hodgkin's lYMPHOMA |
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