Haptoglobin-α subunit as potential Serum biomarker in ovarian cancer: Identification and characterization Using proteomic profiling and mass spectrometry

The objective of this study was to identify and characterize new serum biomarkers in ovarian cancer patients using mass spectrometric protein profiling and specific immunological assays. Serum samples from 80 cancer patients and 91 healthy women were analyzed by surface enhanced laser desorption and...

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Veröffentlicht in:	Clinical cancer research 2003-08, Vol.9 (8), p.2904-2911
Hauptverfasser:	BIN YE, CRAMER, Daniel W, MOK, Samuel C, SKATES, Steven J, GYGI, Steven P, PRATOMO, Vanessa, LANFEI FU, HORICK, Nora K, LICKLIDER, Larry J, SCHORGE, John O, BERKOWITZ, Ross S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences Biomarkers, Tumor - blood Biotin - metabolism Blotting, Western CA-125 Antigen - blood Dimerization Enzyme-Linked Immunosorbent Assay Female Female genital diseases Genital Neoplasms, Female - blood Gynecology. Andrology. Obstetrics Haptoglobins - biosynthesis Humans Mass Spectrometry Medical sciences Molecular Sequence Data Oligonucleotide Array Sequence Analysis Ovarian Neoplasms - blood Ovarian Neoplasms - diagnosis Peptides - chemistry Proteomics - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Time Factors Tumors
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