Carbohydrate transition state mimics: synthesis of imidazolo-Pyrrolidinoses as potential nectrisine surrogates

The syntheses of four glyco-imidazoles, which are pentose-derivatives belonging to the d-series, as well as the syntheses of their l-enantiomers, are reported. Starting from the known linear xylo, lyxo, arabino, and ribo imidazolo-pentoses in both the l- and the d-series, intramolecular Walden inver...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2003-08, Vol.11 (17), p.3559-3568
Hauptverfasser: Tschamber, Théophile, Gessier, François, Dubost, Estelle, Newsome, Jeffery, Tarnus, Céline, Kohler, Josiane, Neuburger, Markus, Streith, Jacques
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Sprache:eng
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