In vitro mechanical compression induces apoptosis and regulates cytokines release in hypertrophic scars

Hypertrophic scars resulting from severe burns are usually treated by continuous elastic compression. Although pressure therapy reaches success rates of 60–85% its mechanisms of action are still poorly understood. In this study, apoptosis induction and release of interleukin‐1β (IL‐1β) and tumor nec...

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Veröffentlicht in:	Wound repair and regeneration 2003-09, Vol.11 (5), p.331-336
Hauptverfasser:	Renò, Filippo, Sabbatini, Maurizio, Lombardi, Francesca, Stella, Maurizio, Pezzuto, Carla, Magliacani, Gilberto, Cannas, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cicatrix, Hypertrophic - metabolism Compressive Strength Dermis - metabolism DNA Fragmentation - physiology Female Humans In Situ Nick-End Labeling In Vitro Techniques Interleukin-1 - metabolism Male Stress, Mechanical Time Factors Tumor Necrosis Factor-alpha - metabolism
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