Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus

The endoplasmic reticulum (ER), similary to other subcompartments of the eukaryotic cell possesses a relatively oxidizing environment. The special milieu of ER lumen is important for many ER‐specific processes (redox protein folding, glycoprotein synthesis, quality control of secreted proteins, anti...

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Veröffentlicht in:	BioFactors (Oxford) 2003, Vol.17 (1-4), p.259-267
Hauptverfasser:	Nardai, Gábor, Korcsmáros, Tamás, Papp, Eszter, Csermely, Péter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diabetes Mellitus Disulfides - chemistry Endoplasmic Reticulum - chemistry Endoplasmic Reticulum - metabolism Humans Membrane Proteins - chemistry Oxidation-Reduction Oxidative Stress Protein Disulfide-Isomerases - chemistry Protein Disulfide-Isomerases - metabolism Protein Folding Sulfhydryl Compounds - chemistry Sulfhydryl Compounds - metabolism
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