Enhanced carotid-cardiac baroreflex response and elimination of orthostatic hypotension 24 hours after acute exercise in paraplegics
To test the hypothesis that an acute bout of maximal exercise can ameliorate orthostatic hypotension consequent to prolonged wheelchair confinement, we evaluated heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure responses during 15 minutes of 70 degrees head-up tilt (HUT) in 10 para...
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| Veröffentlicht in: | Paraplegia 1992-12, Vol.30 (12), p.872-879 |
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| creator | Engelke, K. A. Shea, J. D. Doerr, D. F. Convertino, V. A. |
| description | To test the hypothesis that an acute bout of maximal exercise can ameliorate orthostatic hypotension consequent to prolonged wheelchair confinement, we evaluated heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure responses during 15 minutes of 70 degrees head-up tilt (HUT) in 10 paraplegic subjects 24 hours after arm crank exercise designed to elicit maximal effort, and during a control (no exercise) conditions. Additionally, the carotid baroreceptor stimulus-cardiac response relationship was determined by measurement of R-R interval during external application of graded pressures to the carotid sinuses. One week separated the treatment conditions. The maximum slope of the carotid-cardiac baroreflex response was increased (p = 0.049) by exercise (6.2 +/- 1.7 msec/mmHg) compared to control (3.3 +/- 0.6). During control HUT, HR increased from 61 +/- 1 to 90 +/- 7 bpm (p = 0.001) while SBP decreased from 118 +/- 5 to 106 +/- 9 mmHg (p = 0.025). During HUT 24 hours after exercise, HR increased from 60 +/- 2 to 90 +/- 4 bpm (p = 0.001), but the reduction in SBP was essentially eliminated (116 +/- 5 to 113 +/- 5 mmHg). |
| doi_str_mv | 10.1038/sc.1992.164 |
| format | Article |
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The maximum slope of the carotid-cardiac baroreflex response was increased (p = 0.049) by exercise (6.2 +/- 1.7 msec/mmHg) compared to control (3.3 +/- 0.6). During control HUT, HR increased from 61 +/- 1 to 90 +/- 7 bpm (p = 0.001) while SBP decreased from 118 +/- 5 to 106 +/- 9 mmHg (p = 0.025). 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A.</creatorcontrib><creatorcontrib>Shea, J. D.</creatorcontrib><creatorcontrib>Doerr, D. F.</creatorcontrib><creatorcontrib>Convertino, V. A.</creatorcontrib><title>Enhanced carotid-cardiac baroreflex response and elimination of orthostatic hypotension 24 hours after acute exercise in paraplegics</title><title>Paraplegia</title><addtitle>Paraplegia</addtitle><description>To test the hypothesis that an acute bout of maximal exercise can ameliorate orthostatic hypotension consequent to prolonged wheelchair confinement, we evaluated heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure responses during 15 minutes of 70 degrees head-up tilt (HUT) in 10 paraplegic subjects 24 hours after arm crank exercise designed to elicit maximal effort, and during a control (no exercise) conditions. Additionally, the carotid baroreceptor stimulus-cardiac response relationship was determined by measurement of R-R interval during external application of graded pressures to the carotid sinuses. One week separated the treatment conditions. The maximum slope of the carotid-cardiac baroreflex response was increased (p = 0.049) by exercise (6.2 +/- 1.7 msec/mmHg) compared to control (3.3 +/- 0.6). During control HUT, HR increased from 61 +/- 1 to 90 +/- 7 bpm (p = 0.001) while SBP decreased from 118 +/- 5 to 106 +/- 9 mmHg (p = 0.025). 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A.</creator><creator>Shea, J. D.</creator><creator>Doerr, D. F.</creator><creator>Convertino, V. A.</creator><general>Macmillan</general><scope>CYE</scope><scope>CYI</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19921201</creationdate><title>Enhanced carotid-cardiac baroreflex response and elimination of orthostatic hypotension 24 hours after acute exercise in paraplegics</title><author>Engelke, K. A. ; Shea, J. D. ; Doerr, D. F. ; Convertino, V. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-6e8d98f4efd754cd9d1828425b37d4425664685b21efa94cded706bdce2be1183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Aerospace Medicine</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - physiology</topic><topic>Carotid Arteries - physiopathology</topic><topic>Ergometry</topic><topic>Exercise - physiology</topic><topic>Heart - physiopathology</topic><topic>Heart Rate - physiology</topic><topic>Humans</topic><topic>Hypotension, Orthostatic - physiopathology</topic><topic>Hypotension, Orthostatic - therapy</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Nervous system as a whole</topic><topic>Neurology</topic><topic>Paraplegia - physiopathology</topic><topic>Posture</topic><topic>Pressoreceptors - physiology</topic><topic>Reflex - physiology</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Engelke, K. A.</creatorcontrib><creatorcontrib>Shea, J. D.</creatorcontrib><creatorcontrib>Doerr, D. F.</creatorcontrib><creatorcontrib>Convertino, V. A.</creatorcontrib><collection>NASA Scientific and Technical Information</collection><collection>NASA Technical Reports Server</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Paraplegia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Engelke, K. A.</au><au>Shea, J. D.</au><au>Doerr, D. F.</au><au>Convertino, V. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhanced carotid-cardiac baroreflex response and elimination of orthostatic hypotension 24 hours after acute exercise in paraplegics</atitle><jtitle>Paraplegia</jtitle><addtitle>Paraplegia</addtitle><date>1992-12-01</date><risdate>1992</risdate><volume>30</volume><issue>12</issue><spage>872</spage><epage>879</epage><pages>872-879</pages><issn>0031-1758</issn><issn>1362-4393</issn><eissn>1476-5624</eissn><coden>PRPLBL</coden><abstract>To test the hypothesis that an acute bout of maximal exercise can ameliorate orthostatic hypotension consequent to prolonged wheelchair confinement, we evaluated heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure responses during 15 minutes of 70 degrees head-up tilt (HUT) in 10 paraplegic subjects 24 hours after arm crank exercise designed to elicit maximal effort, and during a control (no exercise) conditions. Additionally, the carotid baroreceptor stimulus-cardiac response relationship was determined by measurement of R-R interval during external application of graded pressures to the carotid sinuses. One week separated the treatment conditions. The maximum slope of the carotid-cardiac baroreflex response was increased (p = 0.049) by exercise (6.2 +/- 1.7 msec/mmHg) compared to control (3.3 +/- 0.6). During control HUT, HR increased from 61 +/- 1 to 90 +/- 7 bpm (p = 0.001) while SBP decreased from 118 +/- 5 to 106 +/- 9 mmHg (p = 0.025). During HUT 24 hours after exercise, HR increased from 60 +/- 2 to 90 +/- 4 bpm (p = 0.001), but the reduction in SBP was essentially eliminated (116 +/- 5 to 113 +/- 5 mmHg).</abstract><cop>Legacy CDMS</cop><pub>Macmillan</pub><pmid>1287541</pmid><doi>10.1038/sc.1992.164</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; NASA Technical Reports Server; Alma/SFX Local Collection |
| subjects | Adult Aerospace Medicine Biological and medical sciences Blood Pressure - physiology Carotid Arteries - physiopathology Ergometry Exercise - physiology Heart - physiopathology Heart Rate - physiology Humans Hypotension, Orthostatic - physiopathology Hypotension, Orthostatic - therapy Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Paraplegia - physiopathology Posture Pressoreceptors - physiology Reflex - physiology Space life sciences |
| title | Enhanced carotid-cardiac baroreflex response and elimination of orthostatic hypotension 24 hours after acute exercise in paraplegics |
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