Chronic treatment with some atypical antidepressants increases the brain level of 3-methoxy-4-hydroxyphenylglycol (MHPG) in rats

We examined the effects of some atypical antidepressants with central antiserotonergic activity (mianserin, trazodone, danitracen, pizotifen), and 5-HT receptor blocking agents (cyproheptadine and metergoline), on whole rat brain levels of the main noradrenaline (NA) metabolite, 3-methoxy-4-hydroxyp...

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Veröffentlicht in:	Psychopharmacology 1981-07, Vol.74 (2), p.187-190
Hauptverfasser:	Przegaliński, E, Kordecka-Magiera, A, Mogilnicka, E, Maj, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - pharmacology Brain Chemistry - drug effects Cyproheptadine - pharmacology Glycols - metabolism Male Metergoline - pharmacology Methoxyhydroxyphenylglycol - metabolism Rats Serotonin Antagonists - pharmacology Time Factors
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