Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

Genetic linkage studies with chromosome 21 DNA markers and mutation analysis of the β–amyloid protein precursor gene located in 21q21.3 have indicated that early–onset Alzheimer's disease (EOAD) is a heterogeneous disorder for which at least one other chromosomal locus exists. We examined two e...

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