Insulinoma
Insulinomas are the most common islet cell tumors and are located almost exclusively in the pancreas. Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localizat...
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Veröffentlicht in: | Current treatment options in oncology 2003-08, Vol.4 (4), p.309-317 |
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description | Insulinomas are the most common islet cell tumors and are located almost exclusively in the pancreas. Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult. Intraoperative palpation and ultrasound remain the gold standard for detection and appropriately planned resection. Although many options are available to treat the patient with malignant and metastatic disease, the mainstay of treatment remains surgery. Laparoscopic ultrasound and enucleation/resection may be increasingly used in the management of patients with insulinoma. |
doi_str_mv | 10.1007/s11864-003-0006-y |
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Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult. Intraoperative palpation and ultrasound remain the gold standard for detection and appropriately planned resection. Although many options are available to treat the patient with malignant and metastatic disease, the mainstay of treatment remains surgery. Laparoscopic ultrasound and enucleation/resection may be increasingly used in the management of patients with insulinoma.</description><identifier>ISSN: 1527-2729</identifier><identifier>EISSN: 1534-6277</identifier><identifier>EISSN: 1534-5277</identifier><identifier>DOI: 10.1007/s11864-003-0006-y</identifier><identifier>PMID: 12943611</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Enucleation ; Humans ; Hypoglycemia ; Insulinoma ; Insulinoma - drug therapy ; Insulinoma - radiotherapy ; Insulinoma - surgery ; Insulinoma - therapy ; Localization ; Metastases ; Multiple endocrine neoplasia ; Neuroendocrine tumors ; Pancreatic cancer ; Patients ; Tumors ; Ultrasonic imaging ; Ultrasound</subject><ispartof>Current treatment options in oncology, 2003-08, Vol.4 (4), p.309-317</ispartof><rights>Current Science Inc. 2003</rights><rights>Current Science Inc 2003.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c268t-b75bf38c204e57a5ffc7a40514afb5147a44834e5946db1d9a7df33f40731bb73</citedby><cites>FETCH-LOGICAL-c268t-b75bf38c204e57a5ffc7a40514afb5147a44834e5946db1d9a7df33f40731bb73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12943611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burns, Andrew R</creatorcontrib><creatorcontrib>Dackiw, Alan P B</creatorcontrib><title>Insulinoma</title><title>Current treatment options in oncology</title><addtitle>Curr Treat Options Oncol</addtitle><description>Insulinomas are the most common islet cell tumors and are located almost exclusively in the pancreas. Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult. Intraoperative palpation and ultrasound remain the gold standard for detection and appropriately planned resection. Although many options are available to treat the patient with malignant and metastatic disease, the mainstay of treatment remains surgery. Laparoscopic ultrasound and enucleation/resection may be increasingly used in the management of patients with insulinoma.</description><subject>Enucleation</subject><subject>Humans</subject><subject>Hypoglycemia</subject><subject>Insulinoma</subject><subject>Insulinoma - drug therapy</subject><subject>Insulinoma - radiotherapy</subject><subject>Insulinoma - surgery</subject><subject>Insulinoma - therapy</subject><subject>Localization</subject><subject>Metastases</subject><subject>Multiple endocrine neoplasia</subject><subject>Neuroendocrine tumors</subject><subject>Pancreatic cancer</subject><subject>Patients</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><subject>Ultrasound</subject><issn>1527-2729</issn><issn>1534-6277</issn><issn>1534-5277</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kEtLAzEQgIMo9qE_wIsXwVs0k8ljc5RitVDwoueQ7CbQso-66R76783SBcGDh5nJkG-G5CPkDtgTMKafE0ChBGUMczBFTxdkDhIFVVzry_HMNeWamxlZpLRnjEvBzDWZATcCFcCcLDZtGupd2zXuhlxFV6dwO9Ul-Vq_fq7e6fbjbbN62dKSq-JIvZY-YlFyJoLUTsZYaieYBOGizzk3osB8Z4SqPFTG6SoiRsE0gvcal-TxvPfQd99DSEfb7FIZ6tq1oRuS1Si5QsAMPvwB993Qt_ltlisl8teNgv8oAMBCK1WYTMGZKvsupT5Ee-h3jetPFpgdZdqzTJtl2lGmPeWZ-2nz4JtQ_U5M9vAHmVJrhQ</recordid><startdate>20030801</startdate><enddate>20030801</enddate><creator>Burns, Andrew R</creator><creator>Dackiw, Alan P B</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20030801</creationdate><title>Insulinoma</title><author>Burns, Andrew R ; 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Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult. Intraoperative palpation and ultrasound remain the gold standard for detection and appropriately planned resection. Although many options are available to treat the patient with malignant and metastatic disease, the mainstay of treatment remains surgery. Laparoscopic ultrasound and enucleation/resection may be increasingly used in the management of patients with insulinoma.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>12943611</pmid><doi>10.1007/s11864-003-0006-y</doi><tpages>9</tpages></addata></record> |
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subjects | Enucleation Humans Hypoglycemia Insulinoma Insulinoma - drug therapy Insulinoma - radiotherapy Insulinoma - surgery Insulinoma - therapy Localization Metastases Multiple endocrine neoplasia Neuroendocrine tumors Pancreatic cancer Patients Tumors Ultrasonic imaging Ultrasound |
title | Insulinoma |
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