Acquisition of an appetitive behavior prevents development of stress-induced neurochemical modifications in rat nucleus accumbens

In rats, exposure to chronic unavoidable stress produces a decrease in dopamine output in the nucleus accumbens shell that is accompanied by a decreased density of the dopamine transporter and an increased activity of the dopamine‐D1 receptor complex. These modifications have been hypothesized to be...

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Veröffentlicht in:	Journal of neuroscience research 2003-08, Vol.73 (4), p.573-580
Hauptverfasser:	Nanni, Giulio, Scheggi, Simona, Leggio, Benedetta, Grappi, Silvia, Masi, Flavio, Rauggi, Riccardo, De Montis, Maria Graziella
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology Adenylyl Cyclases - analysis Analysis of Variance Animals Appetite - drug effects Appetite - physiology Behavior, Animal Benzazepines - pharmacokinetics Binding Sites Brain Chemistry Carbohydrates - pharmacology Cell Count - methods chronic stress Cocaine - analogs & derivatives Cocaine - pharmacokinetics Conditioning, Operant Disease Models, Animal Dopamine - metabolism Dopamine Agonists - pharmacology Dopamine Antagonists - pharmacokinetics dopamine output Dopamine Plasma Membrane Transport Proteins Dopamine Uptake Inhibitors - pharmacokinetics Escape Reaction instrumental behavior Male Maze Learning Membrane Glycoproteins Membrane Transport Proteins - metabolism Microdialysis Nerve Tissue Proteins nucleus accumbens Nucleus Accumbens - chemistry Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Rats Rats, Sprague-Dawley Stress, Physiological - metabolism Stress, Physiological - prevention & control Time Factors Tritium - pharmacokinetics Vanilla - physiology
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