Rapid and slow changes in the human cone electroretinogram during light and dark adaptation
Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes...
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| Veröffentlicht in: | Vision research (Oxford) 1992-11, Vol.32 (11), p.2049-2053 |
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| creator | Peachey, Neal S. Arakawa, Kenji Alexander, Kenneth R. Marchese, Anthony L. |
| description | Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes in the cone ERG during adaptation, responses to stimuli of constant luminance were measured repeatedly during 15 min of exposure to an adapting field of 2.0 log cd/m
2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation. |
| doi_str_mv | 10.1016/0042-6989(92)90066-R |
| format | Article |
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2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation.</description><subject>Adaptation, Ocular - physiology</subject><subject>Biological and medical sciences</subject><subject>Cones</subject><subject>Dark adaptation</subject><subject>Dark Adaptation - physiology</subject><subject>Electroretinogram</subject><subject>Electroretinography</subject><subject>Eye and associated structures. Visual pathways and centers. Vision</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Light</subject><subject>Light adaptation</subject><subject>Photic Stimulation</subject><subject>Photoreceptor Cells - physiology</subject><subject>Reaction Time</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0042-6989</issn><issn>1878-5646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoMo67j6DxRyENFDa5JOd5LLgix-LCwIg548hEpSMxPtTo9J94r_3szOsHvbU0G9T70UDyEvOXvPGe8_MCZF0xtt3hrxzjDW9836EVlxrXTT9bJ_TFZ3yFPyrJRfjDHVCXNGznjLJNNiRX6uYR8DhRRoGaa_1O8gbbHQmOi8Q7pbRkjUTwkpDujnPGWcY5q2GUYalhzTlg5xu5tvGwLk3xQC7GeY45SekycbGAq-OM1z8uPzp--XX5vrb1-uLj9eN75rxdw4aJ0TTmknRWAaOm-gYw5lUFJjaOv_rK5qUCPtTeedQxW4kk7xILA9J2-Ovfs8_VmwzHaMxeMwQMJpKVa1neBKiwrKI-jzVErGjd3nOEL-ZzmzB6f2IMwehFkj7K1Tu65nr079ixsx3B8dJdb89SmH4mHYZEg-ljtMStMprit2ccSwuriJmG3xEZPHEHNVa8MUH_7jP7BZlAU</recordid><startdate>19921101</startdate><enddate>19921101</enddate><creator>Peachey, Neal S.</creator><creator>Arakawa, Kenji</creator><creator>Alexander, Kenneth R.</creator><creator>Marchese, Anthony L.</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19921101</creationdate><title>Rapid and slow changes in the human cone electroretinogram during light and dark adaptation</title><author>Peachey, Neal S. ; Arakawa, Kenji ; Alexander, Kenneth R. ; Marchese, Anthony L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c532t-ba3bb2b78b42d08a5c9a50be4d748ed36980c9a8a5a5c8c95cbbe7d174b71d2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adaptation, Ocular - physiology</topic><topic>Biological and medical sciences</topic><topic>Cones</topic><topic>Dark adaptation</topic><topic>Dark Adaptation - physiology</topic><topic>Electroretinogram</topic><topic>Electroretinography</topic><topic>Eye and associated structures. Visual pathways and centers. Vision</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Light</topic><topic>Light adaptation</topic><topic>Photic Stimulation</topic><topic>Photoreceptor Cells - physiology</topic><topic>Reaction Time</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peachey, Neal S.</creatorcontrib><creatorcontrib>Arakawa, Kenji</creatorcontrib><creatorcontrib>Alexander, Kenneth R.</creatorcontrib><creatorcontrib>Marchese, Anthony L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Vision research (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peachey, Neal S.</au><au>Arakawa, Kenji</au><au>Alexander, Kenneth R.</au><au>Marchese, Anthony L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rapid and slow changes in the human cone electroretinogram during light and dark adaptation</atitle><jtitle>Vision research (Oxford)</jtitle><addtitle>Vision Res</addtitle><date>1992-11-01</date><risdate>1992</risdate><volume>32</volume><issue>11</issue><spage>2049</spage><epage>2053</epage><pages>2049-2053</pages><issn>0042-6989</issn><eissn>1878-5646</eissn><coden>VISRAM</coden><abstract>Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes in the cone ERG during adaptation, responses to stimuli of constant luminance were measured repeatedly during 15 min of exposure to an adapting field of 2.0 log cd/m
2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>1304082</pmid><doi>10.1016/0042-6989(92)90066-R</doi><tpages>5</tpages></addata></record> |
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| subjects | Adaptation, Ocular - physiology Biological and medical sciences Cones Dark adaptation Dark Adaptation - physiology Electroretinogram Electroretinography Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Humans Light Light adaptation Photic Stimulation Photoreceptor Cells - physiology Reaction Time Vertebrates: nervous system and sense organs |
| title | Rapid and slow changes in the human cone electroretinogram during light and dark adaptation |
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