Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy)

Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be...

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Veröffentlicht in:Forensic science international 2003-07, Vol.135 (1), p.48-52
Hauptverfasser: Bini, C., Ceccardi, S., Luiselli, D., Ferri, G., Pelotti, S., Colalongo, C., Falconi, M., Pappalardo, G.
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container_end_page 52
container_issue 1
container_start_page 48
container_title Forensic science international
container_volume 135
creator Bini, C.
Ceccardi, S.
Luiselli, D.
Ferri, G.
Pelotti, S.
Colalongo, C.
Falconi, M.
Pappalardo, G.
description Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI–HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated.
doi_str_mv 10.1016/S0379-0738(03)00167-1
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source MEDLINE; Elsevier ScienceDirect Journals Complete; ProQuest Central
subjects Animals
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
Complementarity Determining Regions - genetics
Deoxyribonucleic acid
DNA
DNA, Mitochondrial - genetics
Forensic sciences
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Genetics, Population
Haplotypes
Humans
Hypervariable regions (HVRs)
Italy
Mitochondrial DNA
Polymorphism
Polymorphism, Genetic
Sequencing
Vertebrata
title Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy)
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