Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy)
Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be...
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Veröffentlicht in: | Forensic science international 2003-07, Vol.135 (1), p.48-52 |
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creator | Bini, C. Ceccardi, S. Luiselli, D. Ferri, G. Pelotti, S. Colalongo, C. Falconi, M. Pappalardo, G. |
description | Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI–HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated. |
doi_str_mv | 10.1016/S0379-0738(03)00167-1 |
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The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI–HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/S0379-0738(03)00167-1</identifier><identifier>PMID: 12893135</identifier><identifier>CODEN: FSINDR</identifier><language>eng</language><publisher>Kidlington: Elsevier Ireland Ltd</publisher><subject>Animals ; Biological and medical sciences ; Classical genetics, quantitative genetics, hybrids ; Complementarity Determining Regions - genetics ; Deoxyribonucleic acid ; DNA ; DNA, Mitochondrial - genetics ; Forensic sciences ; Fundamental and applied biological sciences. Psychology ; Genetics of eukaryotes. 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The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI–HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Complementarity Determining Regions - genetics</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA, Mitochondrial - genetics</subject><subject>Forensic sciences</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics of eukaryotes. 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subjects | Animals Biological and medical sciences Classical genetics, quantitative genetics, hybrids Complementarity Determining Regions - genetics Deoxyribonucleic acid DNA DNA, Mitochondrial - genetics Forensic sciences Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Genetics, Population Haplotypes Humans Hypervariable regions (HVRs) Italy Mitochondrial DNA Polymorphism Polymorphism, Genetic Sequencing Vertebrata |
title | Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy) |
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