Ca2+-independent protein kinase C signalling in mouse eggs during the early phases of fertilization

Protein kinase C (PKC), an enzyme playing a central role in signal transduction pathways, is activated in fertilized mouse eggs downstream of the fertilization Ca2+ signal, to regulate different aspects of egg activation. Given the presence of Ca2+-independent PKC isoforms within the egg, we investi...

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Veröffentlicht in:	The International journal of developmental biology 2003-06, Vol.47 (5), p.327-333
Hauptverfasser:	Tatone, Carla, Delle Monache, Simona, Francione, Antonella, Gioia, Luisa, Barboni, Barbara, Colonna, Rosella
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Chelating Agents - pharmacology Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Enzyme Activation Female Fertilization Immunohistochemistry Male Meiosis Mice Microscopy, Confocal Protein Isoforms Protein Kinase C - chemistry Protein Kinase C - metabolism Protein Kinase C-delta Signal Transduction Spermatozoa - metabolism Spindle Apparatus Time Factors
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