GFAP Promoter Drives Muller Cell-Specific Expression in Transgenic Mice

In an attempt to identify Müller cell-specific promoters and to better understand the gene regulatory mechanisms in retinal glial cells, the expression of the glial fibrillary acidic protein (GFAP) gene was studied in Müller cell cultures and in GFAP-enhanced green fluorescent protein (EGFP) transge...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2003-08, Vol.44 (8), p.3606-3613
Hauptverfasser:	Kuzmanovic, Milena, Dudley, V. Joseph, Sarthy, Vijay P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Ciliary Neurotrophic Factor - pharmacology Eye and associated structures. Visual pathways and centers. Vision Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Glial Fibrillary Acidic Protein - genetics Green Fluorescent Proteins Immunoblotting Luminescent Proteins - genetics Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Transgenic Neurons - metabolism Promoter Regions, Genetic - physiology Recombinant Fusion Proteins Retina - cytology Retina - drug effects Transfection Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
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