Up-Regulation of Urokinase-Type Plasminogen Activator in Corneal Epithelial Cells Induced by Wounding

To investigate the possible role of urokinase-type plasminogen activator (uPA) in corneal epithelial wound healing by examining its expression both in the rabbit corneal epithelium in situ and in rabbit corneal epithelial (RCE) cells in vitro. The rabbit cornea was subjected to mechanical wounding,...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2003-08, Vol.44 (8), p.3332-3338
Hauptverfasser:	Watanabe, Masanao, Yano, Wataru, Kondo, Shoichi, Hattori, Yukio, Yamada, Naoyuki, Yanai, Ryoji, Nishida, Teruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Biological and medical sciences Cell Movement Cells, Cultured Enzyme-Linked Immunosorbent Assay Epithelial Cells - enzymology Epithelium, Corneal - enzymology Epithelium, Corneal - injuries Epithelium, Corneal - pathology Eye Eye Injuries, Penetrating - enzymology Eye Injuries, Penetrating - pathology Fluorescent Antibody Technique, Indirect Gene Expression Regulation, Enzymologic Male Medical sciences Microscopy, Fluorescence Pharmacology. Drug treatments Rabbits Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Up-Regulation Urokinase-Type Plasminogen Activator - genetics Urokinase-Type Plasminogen Activator - metabolism Wound Healing
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