Synaptic plasticity preserved with arachidonic acid diet in aged rats

We examined whether synaptic plasticity was preserved in aged rats administered an arachidonic acid (AA) containing diet. Young male Fischer-344 rats (2 mo of age), and two groups of aged rats of the same strain (2 y of age) who consumed either a control diet or an AA ethyl ester-containing diet for...

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Veröffentlicht in:	Neuroscience research 2003-08, Vol.46 (4), p.453-461
Hauptverfasser:	Kotani, Susumu, Nakazawa, Hiroe, Tokimasa, Takayuki, Akimoto, Kengo, Kawashima, Hiroshi, Toyoda-Ono, Yoshiko, Kiso, Yoshinobu, Okaichi, Hiroshige, Sakakibara, Manabu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - physiology Animals Arachidonic Acid - pharmacology Arachidonic acid diet Correlation coefficient Diet - methods Electric Stimulation Excitatory Postsynaptic Potentials Hippocampus - cytology Hippocampus - drug effects Hippocampus - physiology In Vitro Techniques Lipid analysis Lipids - analysis Long-term potentiation Male Maze Learning - drug effects Neuronal Plasticity - drug effects Pyramidal Cells - drug effects Pyramidal Cells - physiology Rat Rats Rats, Inbred F344 Reaction Time Regression Analysis Synaptic Transmission - drug effects Water maze test
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