Haemoglobin concentration and prognosis in new cases of heart failure
Anaemia is common in severe chronic heart failure and is reported to be a predictor of death. We investigated 552 patients (median age 76 years, range 29–95; 54% men[n=296]), in whom the duration of heart failure was sufficiently short that it would be unlikely to affect haemoglobin concentrations....
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| Veröffentlicht in: | The Lancet (British edition) 2003-07, Vol.362 (9379), p.211-212 |
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| creator | Kalra, Paul R Collier, Timothy Cowie, Martin R Fox, Kevin F Wood, David A Poole-Wilson, Philip A Coats, Andrew JS Sutton, George C |
| description | Anaemia is common in severe chronic heart failure and is reported to be a predictor of death. We investigated 552 patients (median age 76 years, range 29–95; 54% men[n=296]), in whom the duration of heart failure was sufficiently short that it would be unlikely to affect haemoglobin concentrations. By contrast with studies in established chronic heart failure, haemoglobin was not independently associated with prognosis when age and serum creatinine concentration were included in the analysis. The adverse effects of anaemia on survival might be a consequence of chronic heart failure rather than a separate process causing disease progression. |
| doi_str_mv | 10.1016/S0140-6736(03)13912-8 |
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We investigated 552 patients (median age 76 years, range 29–95; 54% men[n=296]), in whom the duration of heart failure was sufficiently short that it would be unlikely to affect haemoglobin concentrations. By contrast with studies in established chronic heart failure, haemoglobin was not independently associated with prognosis when age and serum creatinine concentration were included in the analysis. The adverse effects of anaemia on survival might be a consequence of chronic heart failure rather than a separate process causing disease progression.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(03)13912-8</identifier><identifier>PMID: 12885484</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>London: Elsevier Ltd</publisher><subject>Adult ; Age ; Age Factors ; Aged ; Aged, 80 and over ; Anemia ; Anemia - blood ; Anemia - diagnosis ; Beta blockers ; Biological and medical sciences ; Blood ; Cardiac Output, Low - blood ; Cardiac Output, Low - diagnosis ; Cardiac Output, Low - mortality ; Cardiology. Vascular system ; Cardiovascular disease ; Creatinine ; Creatinine - blood ; Data collection ; Disease Progression ; Female ; Follow-Up Studies ; Health risk assessment ; Heart ; Heart diseases ; Heart failure ; Heart Failure - blood ; Heart Failure - diagnosis ; Heart Failure - mortality ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Hemoglobin ; Hemoglobins - analysis ; Humans ; Male ; Medical prognosis ; Medical sciences ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Renal function ; Survival Analysis</subject><ispartof>The Lancet (British edition), 2003-07, Vol.362 (9379), p.211-212</ispartof><rights>2003 Elsevier Ltd</rights><rights>2003 INIST-CNRS</rights><rights>Copyright Lancet Ltd. 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The adverse effects of anaemia on survival might be a consequence of chronic heart failure rather than a separate process causing disease progression.</description><subject>Adult</subject><subject>Age</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anemia</subject><subject>Anemia - blood</subject><subject>Anemia - diagnosis</subject><subject>Beta blockers</subject><subject>Biological and medical sciences</subject><subject>Blood</subject><subject>Cardiac Output, Low - blood</subject><subject>Cardiac Output, Low - diagnosis</subject><subject>Cardiac Output, Low - mortality</subject><subject>Cardiology. 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| subjects | Adult Age Age Factors Aged Aged, 80 and over Anemia Anemia - blood Anemia - diagnosis Beta blockers Biological and medical sciences Blood Cardiac Output, Low - blood Cardiac Output, Low - diagnosis Cardiac Output, Low - mortality Cardiology. Vascular system Cardiovascular disease Creatinine Creatinine - blood Data collection Disease Progression Female Follow-Up Studies Health risk assessment Heart Heart diseases Heart failure Heart Failure - blood Heart Failure - diagnosis Heart Failure - mortality Heart failure, cardiogenic pulmonary edema, cardiac enlargement Hemoglobin Hemoglobins - analysis Humans Male Medical prognosis Medical sciences Middle Aged Prognosis Proportional Hazards Models Renal function Survival Analysis |
| title | Haemoglobin concentration and prognosis in new cases of heart failure |
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