Measurements of cerebral perfusion and arterial hemodynamics during visual stimulation using TURBO-TILT

Estimation of cerebral blood flow (CBF) in functional perfusion imaging could benefit from a method capable of separating effects of arterial arrival time and trailing edge. To accomplish this, the transfer insensitive labeling technique (TILT) was combined with a train of 13 consecutive acquisition...

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Veröffentlicht in:Magnetic resonance in medicine 2003-08, Vol.50 (2), p.429-433
Hauptverfasser: Hendrikse, Jeroen, Lu, Hanzhang, van der Grond, Jeroen, van Zijl, Peter C.M., Golay, Xavier
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Sprache:eng
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Zusammenfassung:Estimation of cerebral blood flow (CBF) in functional perfusion imaging could benefit from a method capable of separating effects of arterial arrival time and trailing edge. To accomplish this, the transfer insensitive labeling technique (TILT) was combined with a train of 13 consecutive acquisitions, called TURBO‐TILT. Visual activation maps obtained at 13 postlabeling delay times (TI) showed a spatial shift from regions surrounding the arterial vasculature at short TI to brain parenchyma at longer delay times. High baseline CBF and short arrival times were found for the voxels with maximum activation at short TI (
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.10525