Vitamins C and E Improve Endothelial Dysfunction in Intrauterine-Undernourished Rats by Decreasing Vascular Superoxide Anion Concentration

Epidemiological studies suggest that intrauterine undernutrition plays an important role in the development of arterial hypertension in adulthood. Ascorbic acid (vitamin C) and α–tocopherol (vitamin E) have antioxidant properties that could improve redox-sensitive vascular changes associated with hy...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2003-08, Vol.42 (2), p.211-217
Hauptverfasser:	Franco, Maria Carmo P, Akamine, Eliana Hiromi, de Oliveira, Maria Aparecida, Fortes, Zuleica B, Tostes, Rita C. A, Carvalho, Maria Helena C, Nigro, Dorothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antihypertensive agents Antioxidants - therapeutic use Ascorbic Acid - therapeutic use Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Endothelium, Vascular - drug effects Female Hypertension - drug therapy Hypertension - etiology Male Medical sciences Pharmacology. Drug treatments Placental Insufficiency - complications Pregnancy Rats Superoxides - metabolism Vitamin E - therapeutic use
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