Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil
The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months a...
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| Veröffentlicht in: | Research in virology (Paris) 1992, Vol.143 (6), p.423-427 |
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| container_title | Research in virology (Paris) |
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| creator | Nogueira, R.M.R. Miagostovich, M.P. Cavalcanti, S.M.B. Marzochi, K.B.F. Schatzmayr, H.G. |
| description | The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.
L'apparition et la persistance des anticorps IgM ont été étudiées par MAC-ELISA dans 926 cas confirmés d'infection par le virus de la dengue type 1. L'examen des sérums de cas aigus et de convalescents a montré que les IgM apparaissent au début de la maladie et se maintiennent durant 3 mois. Le test MAC-ELISA, comparé à l'inhibition de l'hémagglutination, s'est avéré de grande valeur pour le diagnostic précoce. |
| doi_str_mv | 10.1016/S0923-2516(06)80136-6 |
| format | Article |
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L'apparition et la persistance des anticorps IgM ont été étudiées par MAC-ELISA dans 926 cas confirmés d'infection par le virus de la dengue type 1. L'examen des sérums de cas aigus et de convalescents a montré que les IgM apparaissent au début de la maladie et se maintiennent durant 3 mois. Le test MAC-ELISA, comparé à l'inhibition de l'hémagglutination, s'est avéré de grande valeur pour le diagnostic précoce.</description><identifier>ISSN: 0923-2516</identifier><identifier>DOI: 10.1016/S0923-2516(06)80136-6</identifier><identifier>PMID: 1297178</identifier><language>eng</language><publisher>Paris: Elsevier B.V</publisher><subject>Antibodies, Viral - blood ; Biological and medical sciences ; Brazil - epidemiology ; Dengue ; Dengue - epidemiology ; Dengue - immunology ; Dengue virus ; Dengue Virus - immunology ; Disease Outbreaks ; Enzyme-Linked Immunosorbent Assay ; Epidemiology ; Fundamental and applied biological sciences. Psychology ; Hemagglutination Inhibition Tests ; Humans ; IgM ; Immunoglobulin M - blood ; Immunoglobulin M - immunology ; MAC-ELISA ; Microbiology ; Persistance ; Persistence ; Rio de Janeiro ; Virology ; Virus type 1</subject><ispartof>Research in virology (Paris), 1992, Vol.143 (6), p.423-427</ispartof><rights>1992 Éditions Scientifiques Elsevier, Paris</rights><rights>1993 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-2f3933b14db68587d58549a591383f4e438963c2e47bad9f3c741070346b8d163</citedby><cites>FETCH-LOGICAL-c420t-2f3933b14db68587d58549a591383f4e438963c2e47bad9f3c741070346b8d163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4610890$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1297178$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nogueira, R.M.R.</creatorcontrib><creatorcontrib>Miagostovich, M.P.</creatorcontrib><creatorcontrib>Cavalcanti, S.M.B.</creatorcontrib><creatorcontrib>Marzochi, K.B.F.</creatorcontrib><creatorcontrib>Schatzmayr, H.G.</creatorcontrib><title>Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil</title><title>Research in virology (Paris)</title><addtitle>Res Virol</addtitle><description>The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.
L'apparition et la persistance des anticorps IgM ont été étudiées par MAC-ELISA dans 926 cas confirmés d'infection par le virus de la dengue type 1. L'examen des sérums de cas aigus et de convalescents a montré que les IgM apparaissent au début de la maladie et se maintiennent durant 3 mois. Le test MAC-ELISA, comparé à l'inhibition de l'hémagglutination, s'est avéré de grande valeur pour le diagnostic précoce.</description><subject>Antibodies, Viral - blood</subject><subject>Biological and medical sciences</subject><subject>Brazil - epidemiology</subject><subject>Dengue</subject><subject>Dengue - epidemiology</subject><subject>Dengue - immunology</subject><subject>Dengue virus</subject><subject>Dengue Virus - immunology</subject><subject>Disease Outbreaks</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Epidemiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hemagglutination Inhibition Tests</subject><subject>Humans</subject><subject>IgM</subject><subject>Immunoglobulin M - blood</subject><subject>Immunoglobulin M - immunology</subject><subject>MAC-ELISA</subject><subject>Microbiology</subject><subject>Persistance</subject><subject>Persistence</subject><subject>Rio de Janeiro</subject><subject>Virology</subject><subject>Virus type 1</subject><issn>0923-2516</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLxDAQx3NQfH-EhRxEFKzm1SQ9iYquyorg4xzSZLpEuq0m7YJ-ersP9OgpMPObyZ_fIDSi5IwSKs9fSMF4xnIqj4k80YRymckNtPNb3ka7Kb0TQhRnagttUVYoqvQOGk9gDnXCbYXvp4_YNl0oWx8gYTu1oUkd9tBMe8DzEPuEQ4OfQzvU8INtIMT2FF9F-x3qfbRZ2TrBwfrdQ2-3N6_Xd9nkaXx_fTnJnGCky1jFC85LKnwpda6Vz3UuCpsXlGteCRBcF5I7BkKV1hcVd0pQoggXstSeSr6HjlZ7P2L72UPqzCwkB3U9xGn7ZBTPCVOK_gtSKTmjWg9gvgJdbFOKUJmPGGY2fhlKzMKuWdo1C42GSLO0axZJRusP-nIG_m9qpXboH677NjlbV9E2LqRfTEhKdEEG7GKFDVeAeYBokgvQOPAhguuMb8M_QX4A5KSVMg</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Nogueira, R.M.R.</creator><creator>Miagostovich, M.P.</creator><creator>Cavalcanti, S.M.B.</creator><creator>Marzochi, K.B.F.</creator><creator>Schatzmayr, H.G.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T5</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil</title><author>Nogueira, R.M.R. ; Miagostovich, M.P. ; Cavalcanti, S.M.B. ; Marzochi, K.B.F. ; Schatzmayr, H.G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-2f3933b14db68587d58549a591383f4e438963c2e47bad9f3c741070346b8d163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Antibodies, Viral - blood</topic><topic>Biological and medical sciences</topic><topic>Brazil - epidemiology</topic><topic>Dengue</topic><topic>Dengue - epidemiology</topic><topic>Dengue - immunology</topic><topic>Dengue virus</topic><topic>Dengue Virus - immunology</topic><topic>Disease Outbreaks</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Epidemiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hemagglutination Inhibition Tests</topic><topic>Humans</topic><topic>IgM</topic><topic>Immunoglobulin M - blood</topic><topic>Immunoglobulin M - immunology</topic><topic>MAC-ELISA</topic><topic>Microbiology</topic><topic>Persistance</topic><topic>Persistence</topic><topic>Rio de Janeiro</topic><topic>Virology</topic><topic>Virus type 1</topic><toplevel>online_resources</toplevel><creatorcontrib>Nogueira, R.M.R.</creatorcontrib><creatorcontrib>Miagostovich, M.P.</creatorcontrib><creatorcontrib>Cavalcanti, S.M.B.</creatorcontrib><creatorcontrib>Marzochi, K.B.F.</creatorcontrib><creatorcontrib>Schatzmayr, H.G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Research in virology (Paris)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nogueira, R.M.R.</au><au>Miagostovich, M.P.</au><au>Cavalcanti, S.M.B.</au><au>Marzochi, K.B.F.</au><au>Schatzmayr, H.G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil</atitle><jtitle>Research in virology (Paris)</jtitle><addtitle>Res Virol</addtitle><date>1992</date><risdate>1992</risdate><volume>143</volume><issue>6</issue><spage>423</spage><epage>427</epage><pages>423-427</pages><issn>0923-2516</issn><abstract>The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.
L'apparition et la persistance des anticorps IgM ont été étudiées par MAC-ELISA dans 926 cas confirmés d'infection par le virus de la dengue type 1. L'examen des sérums de cas aigus et de convalescents a montré que les IgM apparaissent au début de la maladie et se maintiennent durant 3 mois. Le test MAC-ELISA, comparé à l'inhibition de l'hémagglutination, s'est avéré de grande valeur pour le diagnostic précoce.</abstract><cop>Paris</cop><pub>Elsevier B.V</pub><pmid>1297178</pmid><doi>10.1016/S0923-2516(06)80136-6</doi><tpages>5</tpages></addata></record> |
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| subjects | Antibodies, Viral - blood Biological and medical sciences Brazil - epidemiology Dengue Dengue - epidemiology Dengue - immunology Dengue virus Dengue Virus - immunology Disease Outbreaks Enzyme-Linked Immunosorbent Assay Epidemiology Fundamental and applied biological sciences. Psychology Hemagglutination Inhibition Tests Humans IgM Immunoglobulin M - blood Immunoglobulin M - immunology MAC-ELISA Microbiology Persistance Persistence Rio de Janeiro Virology Virus type 1 |
| title | Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil |
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