Association of mutation position in polycystic kidney disease 1 ( PKD1) gene and development of a vascular phenotype

Patients with autosomal dominant polycystic kidney disease (ADPKD) are at risk of developing intracranial aneurysms, and subarachnoid haemorrhage is a major cause of death and disability. Familial clustering of intracranial aneurysms suggests that genetic factors are important in the aetiology. We t...

Ausführliche Beschreibung