The Volatile Anesthetic Isoflurane Inhibits the Histamine-Induced Ca2+ Influx in Primary Human Endothelial Cells

Although isoflurane is a known vasodilator, the mechanism of isoflurane-induced vasodilation is not clear. One of the most important systems in this context is the nitric oxide (NO)-mediated vasodilation. The activity of this system is regulated by the agonist-induced Ca2+ influx rather than Ca2+ re...

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Veröffentlicht in:	Anesthesia and analgesia 2003-08, Vol.97 (2), p.430-435
Hauptverfasser:	Tas, Piet W. L., Stöel, Christiane, Roewer, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoquinolines - pharmacology Anesthetics, Inhalation - pharmacology Anesthetics. Neuromuscular blocking agents Biological and medical sciences Calcium - metabolism Calcium Channel Blockers - pharmacology Cells, Cultured Cytoplasm - metabolism Endothelium, Vascular - metabolism Endothelium, Vascular - physiology Histamine - pharmacology Humans Isoflurane - pharmacology Medical sciences Microscopy, Confocal Neuropharmacology Pharmacology. Drug treatments Umbilical Veins Vasodilation - drug effects Vasodilation - physiology
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