Evidence for a Role of MCM (Mini-chromosome Maintenance)5 in Transcriptional Repression of Sub-telomeric and Ty-proximal Genes in Saccharomyces cerevisiae

The MCM (mini-chromosome maintenance) genes have a well established role in the initiation of DNA replication and in the elongation of replication forks in Saccharomyces cerevisiae. In this study we demonstrate elevated expression of sub-telomeric and Ty retrotransposon-proximal genes in two mcm5 st...

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Veröffentlicht in:	The Journal of biological chemistry 2003-07, Vol.278 (30), p.27372-27381
Hauptverfasser:	Dziak, Renata, Leishman, David, Radovic, Maja, Tye, Bik K., Yankulov, Krassimir
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Northern Cell Cycle Proteins - physiology Chromatin - metabolism DNA-Binding Proteins Gene Expression Regulation, Fungal Genome, Fungal Kinetics Micrococcal Nuclease - metabolism Models, Genetic Oligonucleotide Array Sequence Analysis Open Reading Frames Phenotype Retroelements Saccharomyces cerevisiae - metabolism Schizosaccharomyces pombe Proteins Telomere - ultrastructure Temperature Time Factors Transcription, Genetic Transcriptional Activation Up-Regulation
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