Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes
Few studies of bacterial meningitis have focused on the clinical and pathologic features of the illness in adults 1 – 5 . Most large series have included both children and adults, with children accounting for 45 to 87 percent of cases 6 – 16 . Results have rarely been reported according to age group...
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| Veröffentlicht in: | The New England journal of medicine 1993-01, Vol.328 (1), p.21-28 |
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| container_title | The New England journal of medicine |
| container_volume | 328 |
| creator | Durand, Marlene L Calderwood, Stephen B Weber, David J Miller, Samuel I Southwick, Frederick S Caviness, Verne S Swartz, Morton N |
| description | Few studies of bacterial meningitis have focused on the clinical and pathologic features of the illness in adults
1
–
5
. Most large series have included both children and adults, with children accounting for 45 to 87 percent of cases
6
–
16
. Results have rarely been reported according to age group in these studies. To characterize acute bacterial meningitis in adults, we reviewed our experience at Massachusetts General Hospital over a 27-year period, from 1962 through 1988. We focused on several questions of particular current interest: What are the differences between nosocomial and community-acquired meningitis, and has the relative frequency of . . . |
| doi_str_mv | 10.1056/NEJM199301073280104 |
| format | Article |
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1
–
5
. Most large series have included both children and adults, with children accounting for 45 to 87 percent of cases
6
–
16
. Results have rarely been reported according to age group in these studies. To characterize acute bacterial meningitis in adults, we reviewed our experience at Massachusetts General Hospital over a 27-year period, from 1962 through 1988. We focused on several questions of particular current interest: What are the differences between nosocomial and community-acquired meningitis, and has the relative frequency of . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199301073280104</identifier><identifier>PMID: 8416268</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Acute Disease ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacilli ; Bacteria ; Bacterial diseases ; Bacterial diseases of the nervous system. Bacterial myositis ; Biological and medical sciences ; Boston ; Central nervous system ; Cerebrospinal fluid ; Children & youth ; Cross Infection - mortality ; Gram-negative bacilli ; Gram-Negative Bacterial Infections - cerebrospinal fluid ; Gram-Negative Bacterial Infections - mortality ; Gram-Negative Bacterial Infections - transmission ; Hospital Mortality ; Hospitals ; Human bacterial diseases ; Humans ; Illnesses ; Infectious diseases ; Listeria monocytogenes ; Medical sciences ; Meningitis ; Meningitis, Bacterial - cerebrospinal fluid ; Meningitis, Bacterial - mortality ; Middle Aged ; Mortality ; Nervous system ; Neutrophils ; Organisms ; Pneumococcal Infections - mortality ; Recurrence ; Risk Factors ; Seizures ; Seizures - etiology</subject><ispartof>The New England journal of medicine, 1993-01, Vol.328 (1), p.21-28</ispartof><rights>Copyright © 1993 Massachusetts Medical Society. All rights reserved.</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c621t-9e30fd2a63b705bba777fe255b58d366c17cae49687dec7f720aa9e0a39513143</citedby><cites>FETCH-LOGICAL-c621t-9e30fd2a63b705bba777fe255b58d366c17cae49687dec7f720aa9e0a39513143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199301073280104$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199301073280104$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4521939$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8416268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Durand, Marlene L</creatorcontrib><creatorcontrib>Calderwood, Stephen B</creatorcontrib><creatorcontrib>Weber, David J</creatorcontrib><creatorcontrib>Miller, Samuel I</creatorcontrib><creatorcontrib>Southwick, Frederick S</creatorcontrib><creatorcontrib>Caviness, Verne S</creatorcontrib><creatorcontrib>Swartz, Morton N</creatorcontrib><title>Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Few studies of bacterial meningitis have focused on the clinical and pathologic features of the illness in adults
1
–
5
. Most large series have included both children and adults, with children accounting for 45 to 87 percent of cases
6
–
16
. Results have rarely been reported according to age group in these studies. To characterize acute bacterial meningitis in adults, we reviewed our experience at Massachusetts General Hospital over a 27-year period, from 1962 through 1988. We focused on several questions of particular current interest: What are the differences between nosocomial and community-acquired meningitis, and has the relative frequency of . . .</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Bacilli</subject><subject>Bacteria</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the nervous system. Bacterial myositis</subject><subject>Biological and medical sciences</subject><subject>Boston</subject><subject>Central nervous system</subject><subject>Cerebrospinal fluid</subject><subject>Children & youth</subject><subject>Cross Infection - mortality</subject><subject>Gram-negative bacilli</subject><subject>Gram-Negative Bacterial Infections - cerebrospinal fluid</subject><subject>Gram-Negative Bacterial Infections - mortality</subject><subject>Gram-Negative Bacterial Infections - transmission</subject><subject>Hospital Mortality</subject><subject>Hospitals</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Illnesses</subject><subject>Infectious diseases</subject><subject>Listeria monocytogenes</subject><subject>Medical sciences</subject><subject>Meningitis</subject><subject>Meningitis, Bacterial - cerebrospinal fluid</subject><subject>Meningitis, Bacterial - mortality</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Nervous system</subject><subject>Neutrophils</subject><subject>Organisms</subject><subject>Pneumococcal Infections - mortality</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Seizures</subject><subject>Seizures - etiology</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkctqHDEQRYVxmIztfIExCByyCR1LKj13npjJC08CIV43anV10NCPcas7IX9vhRm8CMGuTS3uubeoKkLOOXvHmdJXX9dfNtw5YJwZEDY3eUSWXAEUUjJ9TJaMCVtI4-AlOUlpy3Jx6RZkYSXXQtsluV6FeUL63ocJx-hbusE-9j_jFBONPV3VczslWhR0Rb_jr4i_6dBQ6YCudzENNaYz8qLxbcJXh35K7j6sf9x8Km6_ffx8s7otghZ8KhwCa2rhNVSGqaryxpgGhVKVsjVoHbgJHqXT1tQYTGME894h8-AUBy7hlLzZ5-7G4X7GNJVdTAHb1vc4zKk0kM1CPQ9ybYWRABm8_AfcDvPY5yVK7qxkRgOzmYI9FcYhpRGbcjfGzo9_Ss7Kv28o__OG7Lo4ZM9Vh_Wj53D3rL8-6D4F3zaj70NMj5hUgjtwGXu7x7oulT1uuyeHPgC9U5cl</recordid><startdate>19930107</startdate><enddate>19930107</enddate><creator>Durand, Marlene L</creator><creator>Calderwood, Stephen B</creator><creator>Weber, David J</creator><creator>Miller, Samuel I</creator><creator>Southwick, Frederick S</creator><creator>Caviness, Verne S</creator><creator>Swartz, Morton N</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19930107</creationdate><title>Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes</title><author>Durand, Marlene L ; Calderwood, Stephen B ; Weber, David J ; Miller, Samuel I ; Southwick, Frederick S ; Caviness, Verne S ; Swartz, Morton N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c621t-9e30fd2a63b705bba777fe255b58d366c17cae49687dec7f720aa9e0a39513143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Bacilli</topic><topic>Bacteria</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the nervous system. Bacterial myositis</topic><topic>Biological and medical sciences</topic><topic>Boston</topic><topic>Central nervous system</topic><topic>Cerebrospinal fluid</topic><topic>Children & youth</topic><topic>Cross Infection - mortality</topic><topic>Gram-negative bacilli</topic><topic>Gram-Negative Bacterial Infections - cerebrospinal fluid</topic><topic>Gram-Negative Bacterial Infections - mortality</topic><topic>Gram-Negative Bacterial Infections - transmission</topic><topic>Hospital Mortality</topic><topic>Hospitals</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Illnesses</topic><topic>Infectious diseases</topic><topic>Listeria monocytogenes</topic><topic>Medical sciences</topic><topic>Meningitis</topic><topic>Meningitis, Bacterial - cerebrospinal fluid</topic><topic>Meningitis, Bacterial - mortality</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Nervous system</topic><topic>Neutrophils</topic><topic>Organisms</topic><topic>Pneumococcal Infections - 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1
–
5
. Most large series have included both children and adults, with children accounting for 45 to 87 percent of cases
6
–
16
. Results have rarely been reported according to age group in these studies. To characterize acute bacterial meningitis in adults, we reviewed our experience at Massachusetts General Hospital over a 27-year period, from 1962 through 1988. We focused on several questions of particular current interest: What are the differences between nosocomial and community-acquired meningitis, and has the relative frequency of . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>8416268</pmid><doi>10.1056/NEJM199301073280104</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1993-01, Vol.328 (1), p.21-28 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73496254 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Acute Disease Adolescent Adult Aged Aged, 80 and over Bacilli Bacteria Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Boston Central nervous system Cerebrospinal fluid Children & youth Cross Infection - mortality Gram-negative bacilli Gram-Negative Bacterial Infections - cerebrospinal fluid Gram-Negative Bacterial Infections - mortality Gram-Negative Bacterial Infections - transmission Hospital Mortality Hospitals Human bacterial diseases Humans Illnesses Infectious diseases Listeria monocytogenes Medical sciences Meningitis Meningitis, Bacterial - cerebrospinal fluid Meningitis, Bacterial - mortality Middle Aged Mortality Nervous system Neutrophils Organisms Pneumococcal Infections - mortality Recurrence Risk Factors Seizures Seizures - etiology |
| title | Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes |
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