The effect of estrous cycle and buthionine sulfoximine on glutathione release from the in vitro perfused rat ovary

There is little known regarding the intracellular mechanisms of modification of damage in the ovary. Ovarian perfusion of en block dissections of the rat right ovary with aorta and vena cava were done to determine (a) if glutathione (GSH) is released by the ovary, (b) if the release is cycle depende...

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Veröffentlicht in:	Reproductive toxicology (Elmsford, N.Y.) N.Y.), 1992, Vol.6 (6), p.533-539
Hauptverfasser:	Clague, Nicholas, Sevcik, Margaret, Stuart, Gavin, Brännström, Mats, Janson, Per Olof, Jarrell, John F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Buthionine Sulfoximine Estrus - physiology Female General aspects. Methods Glutamate-Cysteine Ligase - antagonists & inhibitors glutathione Glutathione - metabolism In Vitro Techniques Lactates - metabolism Lactic Acid Medical sciences Methionine Sulfoximine - analogs & derivatives Methionine Sulfoximine - pharmacology ovary Ovary - drug effects Ovary - metabolism Perfusion Pyruvates - metabolism Pyruvic Acid Rats Rats, Sprague-Dawley Toxicology
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