Pharmacokinetic comparison of fast-disintegrating and conventional tablet formulations of risperidone in healthy volunteers

Background: Difficulties with and resistance to tablet-taking are common in all patient groups and can exacerbate compliance problems and undermine treatment efficacy. In recent years, rapidly dissolving oral drug formulations have been developed to overcome problems related to swallowing difficulti...

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Veröffentlicht in:	Clinical therapeutics 2003-06, Vol.25 (6), p.1687-1699
Hauptverfasser:	van Schaick, Erno A., Lechat, Philippe, Remmerie, Bart M.M., Ko, Grant, Lasseter, Kenneth C., Mannaert, Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - blood Antipsychotic Agents - pharmacokinetics Antipsychotics Area Under Curve Bioavailability Bioequivalence Biological and medical sciences Biological Availability Chemistry, Pharmaceutical Cross-Over Studies Dementia Drug delivery systems Drug dosages fast-disintegrating tablet Female healthy volunteers Humans Isoxazoles - blood Male Medical sciences Metabolic Clearance Rate Middle Aged Neuropharmacology Paliperidone Palmitate pharmacokinetics Pharmacology. Drug treatments Psychiatry Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Psychotropic drugs Pyrimidines - blood R&D Radioimmunoassay Research & development risperidone Risperidone - blood Risperidone - pharmacokinetics Schizophrenia Tablets Therapeutic Equivalency Time Factors
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