Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation

Human papillomavirus (HPV) infections play a crucial role in the pathogenesis of cervical neoplasia. Insights into the mechanisms by which HPV infection can, in a small numbers of cases, result in malignancy, comes from the observation that three proteins encoded by high-risk genital HPVs, E6, E7 an...

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Veröffentlicht in:	Oncogene 2003-08, Vol.22 (33), p.5201-5207
Hauptverfasser:	Fehrmann, Frauke, Laimins, Laimonis A
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell activation Cell Biology Cell cycle Cell Differentiation Cell Division Cell immortalization Cell Transformation, Neoplastic Cervical cancer Epithelial cells Epithelial Cells - virology Genome, Viral Genomes Human Genetics Human papillomavirus Humans Immortalization Infections Internal Medicine Malignancy Medicine Medicine & Public Health Models, Genetic Oncogene Proteins, Viral - physiology Oncology Papillomaviridae Papillomaviridae - pathogenicity Proteins review Telomerase Transformed cells Womens health
Online-Zugang:	Volltext
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