Interleukin-6 mediates lipopolysaccharide-induced nuclear STAT3 translocation in astrocytes of rat sensory circumventricular organs

Pyrogenic treatment with lipopolysaccharide (LPS) or interleukin-6 (IL-6) induces nuclear STAT3 translocation in the vascular organ of the laminae terminalis (OVLT) and the subfornical organ (SFO). STAT3 immunohistochemistry was combined with the detection of marker proteins (glial, neuronal, endoth...

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Veröffentlicht in:	Brain research 2003-08, Vol.980 (1), p.151-155
Hauptverfasser:	Harré, Eva-Maria, Roth, Joachim, Gerstberger, Rüdiger, Hübschle, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism Biological and medical sciences Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cytokine DNA-Binding Proteins - metabolism Fever Fever - metabolism Fundamental and applied biological sciences. Psychology Glia Hypothalamus - metabolism Immunohistochemistry Interleukin-6 - metabolism Lipopolysaccharides - metabolism Male Rats Rats, Wistar Signal transducer and activator of transcription STAT3 Transcription Factor Subfornical organ Subfornical Organ - metabolism Trans-Activators - metabolism Vascular organ of the laminae terminalis Vertebrates: nervous system and sense organs
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