Integrins, cations and ligands: making the connection

Integrins are cell adhesion receptors that couple extracellular divalent cation‐dependent recognition events with intracellular mechanical and biochemical responses and vice versa, thus affecting every function of nucleated cells. The structural basis of this bidirectional signaling and its dependen...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2003-07, Vol.1 (7), p.1642-1654
Hauptverfasser:	Xiong, J‐P., Stehle, T., Goodman, S. L., Arnaout, M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	activation Animals Cations cell adhesion Crystallography, X-Ray Humans integrins Integrins - chemistry Integrins - metabolism Ligands Models, Biological Models, Molecular Protein Binding Protein Structure, Quaternary Protein Structure, Tertiary Signal Transduction therapeutics
Online-Zugang:	Volltext
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