High titers of autoantibodies to tissue factor pathway inhibitor are associated with the antiphospholipid syndrome

As the activity of the tissue factor pathway inhibitor (TFPI) may be impaired in patients with antiphospholipid antibodies (aPL), 162 aPL patients were evaluated for autoantibodies to recombinant TFPI (anti‐TFPI) using an optimized ELISA. Anti‐TFPI (>18 U mL−1 for IgG and/or > 15 U mL−1 for Ig...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2003-04, Vol.1 (4), p.718-724
Hauptverfasser:	Forastiero, R. R., Martinuzzo, M. E., Broze, G. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over antiphospholipid syndrome Antiphospholipid Syndrome - immunology Autoantibodies - blood Case-Control Studies Child Child, Preschool Enzyme-Linked Immunosorbent Assay Factor Xa - metabolism Factor Xa Inhibitors Female Humans Immunoglobulin G - blood Immunoglobulin M - blood Lipoproteins - immunology Male Middle Aged Phospholipids - pharmacology Recombinant Proteins - immunology thrombosis tissue factor pathway inhibitor
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