The regulation and activation potential of autoreactive B cells

Anti-double-stranded DNA (dsDNA) B cells persist even in nonautoimmune- prone animals. In this review, we summarize data regarding the activation potential of these cells. Provision of cognate CD4 T cell help to anti-dsDNA B cells in nonautoimmune mice not only drives their maturation and entry into...

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Veröffentlicht in:	Immunologic research 2003-01, Vol.27 (2-3), p.219-234
Hauptverfasser:	Fields, Michele L, Seo, Su-Jean, Nish, Simone A, Tsai, Jeff H, Caton, Andrew J, Erikson, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-DNA antibodies Antibodies, Antinuclear - immunology Autoimmunity B-Lymphocytes - immunology Cellular biology DNA - immunology Immune system Immunology Lymphocyte Activation - immunology Lymphocyte Cooperation - immunology Mice T-Lymphocytes - immunology
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