Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins

This study examines the spreading and adhesion of human umbilical vein endothelial cells (HUVEC) on artificial extracellular matrix (aECM) proteins containing sequences derived from elastin and fibronectin. Three aECM variants were studied: aECM 1 contains lysine residues periodically spaced within...

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Veröffentlicht in:	Biomaterials 2003-10, Vol.24 (23), p.4245-4252
Hauptverfasser:	Heilshorn, Sarah C., DiZio, Kathleen A., Welsh, Eric R., Tirrell, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biocompatible Materials - chemistry Cell Adhesion Cells, Cultured Elastin - metabolism Endothelial cell Endothelial Cells - cytology Endothelium, Vascular - cytology Extracellular matrix Extracellular Matrix - metabolism Fibronectins - chemistry Fibronectins - metabolism Humans Lipopolysaccharides - chemistry Lysine - chemistry Microscopy, Phase-Contrast Molecular Sequence Data Plasminogen Activator Inhibitor 1 - metabolism Protein Binding Protein design Protein Structure, Tertiary Sequence Homology, Amino Acid Stress, Mechanical Tissue Plasminogen Activator - metabolism Vascular graft
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