Fetal HLA typing in β thalassaemia: implications for haemopoietic stem-cell transplantation

Stem-cell transplantation can cure β thalassaemia. We aimed to assess whether fetal HLA typing done early in the pregnancy of couples who were at risk of β thalassaemia could provide an alternative to pregnancy termination if the prospect of a bone-marrow transplantation from a family member was ava...

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Veröffentlicht in:	The Lancet (British edition) 2003-07, Vol.362 (9377), p.41-42
Hauptverfasser:	Orofino, Maria Grazia, Argiolu, Francesca, Sanna, Maria Adele, Rosatelli, Maria Cristina, Tuveri, Teresa, Scalas, Maria Teresa, Badiali, Manuela, Cossu, Paola, Puddu, Rosalba, Lai, Maria Eliana, Cao, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Thalassemia - diagnosis beta-Thalassemia - immunology beta-Thalassemia - therapy Fetal Diseases - diagnosis Fetal Diseases - immunology Fetal Diseases - therapy Genetic Counseling Hematopoietic Stem Cell Transplantation Histocompatibility Testing - ethics Humans Prenatal Diagnosis - ethics Risk Factors Siblings
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