The gene-protein database of Escherichia coli: Edition 5

The gene‐protein database of Escherichia coli is both an index relating a gene to its protein product on two‐dimensional gels, and a catalog of information about the function, regulation, and genetics of individual proteins obtained from two‐dimensional gel analysis or collated from the literature....

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Veröffentlicht in:Electrophoresis 1992, Vol.13 (1), p.1014-1054
Hauptverfasser: Vanbogelen, Ruth A., Sankar, Pushpam, Clark, Robert L., Bogan, Jacqueline A., Neidhardt, Frederick C.
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container_end_page 1054
container_issue 1
container_start_page 1014
container_title Electrophoresis
container_volume 13
creator Vanbogelen, Ruth A.
Sankar, Pushpam
Clark, Robert L.
Bogan, Jacqueline A.
Neidhardt, Frederick C.
description The gene‐protein database of Escherichia coli is both an index relating a gene to its protein product on two‐dimensional gels, and a catalog of information about the function, regulation, and genetics of individual proteins obtained from two‐dimensional gel analysis or collated from the literature. Edition 5 has 102 new entries–a 15% increase in the number of annotated two‐dimensional gel spots. The large increase in this edition was accomplished in part by the use of a new method for expression analysis of ordered segments of the E. coli genome, which has resulted in linking 50 gel spots to their genes (or open reading frames) and another 45 to specific regions of the chromosome awaiting the availability of DNA sequence information. Communication of information from the scientific community resulted in additional identifications and regulatory information. To increase accessibility of the database it has been placed in the repository at the National Center for Biotechnology Information (NCBI) at the National Library of Medicine under the name ECO2DBASE. It will be updated twice yearly. This edition of the gene‐protein database is estimated to contain entries for one‐sixth of the protein‐encoding genes of E. coli.
doi_str_mv 10.1002/elps.11501301203
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Bacterial Proteins - chemistry
Bacterial Proteins - genetics
Databases, Factual
Electrophoresis, Gel, Two-Dimensional
Escherichia coli - genetics
Genes, Bacterial - genetics
title The gene-protein database of Escherichia coli: Edition 5
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