Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil

Mutations in the p53 and retinoblastoma (pRb) pathways associated with the use of tobacco and alcohol are common in squamous cell carcinoma (SCC) of the head and neck. Cell cycle proteins are also affected by human papillomavirus (HPV), which may also have an aetiological role in cancers at particul...

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Veröffentlicht in:	International journal of cancer 2003-09, Vol.106 (4), p.553-558
Hauptverfasser:	Li, Wei, Thompson, Carol H., O'Brien, Christopher J., McNeil, Edward B., Scolyer, Richard A., Cossart, Yvonne E., Veness, Michael J., Walker, D. Murray, Morgan, Gary J., Rose, Barbara R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - metabolism Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology Cell Cycle Proteins - metabolism cyclin D1 DNA, Viral - analysis Female Humans Immunoenzyme Techniques Male Medical sciences Middle Aged Otorhinolaryngology. Stomatology p21 p27 p53 Papillomaviridae - physiology papillomavirus Papillomavirus Infections - metabolism Papillomavirus Infections - virology pRb Prognosis Survival Rate tonsil cancer Tonsillar Neoplasms - metabolism Tonsillar Neoplasms - pathology Tonsillar Neoplasms - virology Tumor Virus Infections - metabolism Tumor Virus Infections - virology Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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